An authorized generic of Tofranil-PM was sold before, but it isn’t sold now. Ask your pharmacist whether a regular generic (imipramine pamoate) is available.
Source: FDA, updated October 30, 2026
How to pay the least
From
$80.70 for 30 capsules delivered ($75.45 plus $5.25 shipping), any strength
Generic imipramine pamoate from Cost Plus Drugs, by mail
- Make a free account on costplusdrugs.com. Ask your prescriber to send the prescription there, or Cost Plus Drugs can transfer it.Open Cost Plus Drugs
- Order generic imipramine pamoate. It comes by mail.
Need it today? From $84.07 for 30 capsules at CVS with the free Optum Perks coupon. Show the free coupon there. It can’t be used with insurance.
Get the free Optum Perks couponA regular generic has the same active ingredient as Tofranil-PM, and the FDA requires it to work the same way.
Compare every option
Question
Brand nameTofranil-PM
Authorized genericimipramine pamoate
Regular genericimipramine pamoate
What you’d pay
Not soldNo longer sold
Not soldNo longer sold
Same as Tofranil-PM?
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–
Same active ingredientFillers and dyes can differ
Details for each option
Details for
Brand nameNot sold
Tofranil-PM itself isn’t sold as a prescription anymore. Its generic versions, if any, are in the other tabs.
Authorized genericNot sold now
Regular genericWhere to buy it
Pharmacies’ own cash prices for generic imipramine pamoate, lowest first.
Pick up in storeDelivered
- Delivered: Cost Plus Drugs $75.45for 30 capsules75 mg, 100 mg, 125 mg, 150 mgPlus $5.25 shipping
- Pick up in store: CVS Pharmacy + Optum Perks $84.07for 30 capsules100 mgFree Optum Perks coupon · not with insuranceFind the nearest store
- Delivered: Amazon Pharmacy from $101.60for 30 capsules75 mg, 100 mg, 125 mg $101.60 · 150 mg $311.30Prime members only · $139 a year · Free delivery · Prime price: limits on some medicines if you're over 65 or have Medicare, Medicaid or TRICARE
- Pick up in store: Walgreens + Optum Perks $113for 30 capsules100 mgFree Optum Perks coupon · not with insuranceFind the nearest store
From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.
About these prices
Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.
Regular genericWho makes it
2 companies sell a generic of Tofranil-PM that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.
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Hikma Pharmaceuticals75 mg, 100 mg, 125 mg, 150 mg
Has dyes: FD&C Blue No. 1, FD&C Red No. 40, FD&C Yellow No. 6, D&C Yellow No. 10, FD&C Yellow No. 5
How it looks, what’s in it, NDCs
75 mg Brown, capsule, 18 mm, marked “54 / 591”
Package NDC Bottle of 30 0054-0273-13 100 mg Yellow, capsule, 19 mm, marked “54 / 758”
Package NDC Bottle of 30 0054-0274-13 125 mg Ivory, capsule, 19 mm, marked “54 / 466”
Package NDC Bottle of 30 0054-0275-13 150 mg Brown, capsule, 22 mm, marked “54 / 161”
Package NDC Bottle of 30 0054-0276-13 Inactive ingredients: silicon dioxide, FD&C Blue No. 1, FD&C Red No. 40, FD&C Yellow No. 6, ferrosoferric oxide, magnesium stearate, starch, corn, sodium starch glycolate type a potato, talc, titanium dioxide, gelatin, D&C Yellow No. 10, FD&C Yellow No. 5
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Lupin Pharmaceuticals75 mg, 100 mg, 125 mg, 150 mg
Has dyes: FD&C Blue No. 1, FD&C Red No. 40, FD&C Yellow No. 6, D&C Yellow No. 10
How it looks, what’s in it, NDCs
75 mg Brown/brown, capsule, 18 mm, marked “LU / U01”
Package NDC Bottle of 30 68180-314-06 100 mg Brown/dark yellow, capsule, 19 mm, marked “LU / U02”
Package NDC Bottle of 30 68180-315-06 125 mg Brown/light yellow, capsule, 19 mm, marked “LU / U03”
Package NDC Bottle of 30 68180-316-06 150 mg Brown/brown, capsule, 21 mm, marked “LU / U04”
Package NDC Bottle of 30 68180-317-06 Inactive ingredients: FD&C Blue No. 1, FD&C Red No. 40, FD&C Yellow No. 6, gelatin, magnesium stearate, sodium lauryl sulfate, starch, corn, talc, titanium dioxide, D&C Yellow No. 10
Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.
What it’s used for
What the FDA label says
For the relief of symptoms of depression. Endogenous depression is more likely to be alleviated than other depressive states. One to three weeks of treatment may be needed before optimal therapeutic effects are evident.
Source: the FDA label for Imipramine Pamoate (Hikma Pharmaceuticals USA Inc), May 30, 2025. Full label on DailyMed
Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/tofranil-pm/