How do you pay?

How to pay the least

Lowest posted price

$40 a prescription

Tolak from Hill Dermaceuticals, without insurance.

  1. Sign up for Hill Derm Pharmacy direct cash price.Sign up on hilldermpharmacy.com 

Sold only in a different form, strength or formula. Switching to one would need a new prescription, so ask your prescriber whether it could work for you.

Compare every option

Question
Brand nameTolak
Authorized genericfluorouracil
Regular genericfluorouracil
What you’d pay
Cash price$40a prescription from the maker
Not soldThere isn’t one
Other forms onlyAsk your doctor
Same as Tolak?
The original
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Brand nameThe maker’s cash price

Hill Derm Pharmacy direct cash price

Cash price from Hill Dermaceuticals

No insurance $40 a prescription

Sign up on hilldermpharmacy.com 

In the maker’s words

“Price: $40 Cash for All Patients, Includes Shipping…”

From the maker’s offer on hilldermpharmacy.com, checked November 2, 2026. Check the maker’s page for who can use it.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s price above. You can usually use one or the other on a fill, not both.

Brand nameWith a free discount coupon

Optum Perks, Optum’s free discount coupon, lists these prices for Tolak without insurance. Show the coupon from its page at the pharmacy; it can’t be used with insurance.

From Optum Perks, read November 2, 2026, with no location set. Its page opens on this dose; other doses and pharmacies near you are priced there too. With insurance, check your co-pay first: it may be lower.

Authorized genericNot sold

There isn’t one. An authorized generic is Tolak itself, from the same company, sold without the brand name, and usually for less. For now Tolak is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Sold only in a different form, strength or formula. Switching to one would need a new prescription, so ask your prescriber whether it could work for you. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

Tolak (fluorouracil) Cream, 4%, is a nucleoside metabolic inhibitor indicated for the topical treatment of actinic keratosis lesions of the face, ears, and scalp.

Source: the FDA label for Tolak (HILL DERMACEUTICALS, INC.), September 6, 2022. Full label on DailyMed 

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