Tpoxx

Generic name: tecovirimat

Used for: Smallpox

How do you pay?

How to pay the least

Ask for the cash price

Tpoxx

We didn’t find one.

  1. Ask your pharmacy for Tpoxx’s cash price, and one or two other pharmacies too.

Compare every option

Question
Brand nameTpoxx
Authorized generictecovirimat
Regular generictecovirimat
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldNone found
Same as Tpoxx?
The original
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Brand nameNo maker’s card

We didn’t find a savings card or cash price from Tpoxx’s maker. Ask the pharmacy for Tpoxx’s cash price. With insurance, ask what your plan charges.

Authorized genericNot sold

There isn’t one. An authorized generic is Tpoxx itself, from the same company, sold without the brand name, and usually for less. For now Tpoxx is the only choice; ask the pharmacy for its cash price, or your plan what it charges.

Regular genericNot sold

We didn’t find one. Generics usually come once the brand’s patents and exclusivity end. Until then, ask the pharmacy for Tpoxx’s cash price, or your plan what it charges.

What it’s used for

What the FDA label says

TPOXX is an inhibitor of the orthopoxvirus VP37 envelope wrapping protein and is indicated for the treatment of human smallpox disease in adults and pediatric patients weighing at least 3 kg.

Limitations of Use:

  • The effectiveness of TPOXX for treatment of smallpox disease has not been determined in humans because adequate and well-controlled field trials have not been feasible, and inducing smallpox disease in humans to study the drug’s efficacy is not ethical.
  • TPOXX efficacy may be reduced in immunocompromised patients based on studies demonstrating reduced efficacy in immunocompromised animal models.

Source: the FDA label for Tpoxx (SIGA Technologies, Inc.), December 31, 2025. Full label on DailyMed 

Good to know

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/tpoxx/