Brand-name prescription

Tri-Luma

fluocinolone acetonide, hydroquinone, and tretinoin

Compare your options

CompareTri-LumaBrand nameAuthorized genericWithout the Tri-Luma nameRegular genericfluocinolone acetonide, hydroquinone, and tretinoin
What pharmacies pay$235per 30 g tubeNot soldNot sold
Same as Tri-Luma?The original––
Ways to saveMaker’s cardas little as $20 for 30 gwith commercial insurance––
With insuranceYour plan’s brand co-pay––

No authorized generic: There isn’t one.

No regular generic: No generic is sold yet.

Prices are the average U.S. drugstores pay (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

The maker’s savings card

Rx Maker’s savings card Galderma

Galderma CAREConnect Patient Savings Card

With commercial insurance

as little as $20 for 30 g

Paying cash, no insurance

from $90 for 30 g

Get it on galdermacc.com

In the maker’s words

“TRI-LUMA® (fluocinolone acetonide 0.01%, 30 g $20 $90 hydroquinone 4%, tretinoin 0.05%) Cream…”

From the maker’s offer on galdermacc.com, checked September 25, 2026. What you pay depends on your plan. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Before you use a discount card

Discount cards like GoodRx take money off the pharmacy’s cash price. For a brand-name drug, that price is often still high. With commercial insurance, Tri-Luma’s own card may bring it to as little as $20 for 30 g. Paying cash, the maker’s own price is from $90 for 30 g.

Look up the discount-card price, then compare it with this estimate. You can use a maker’s card or a discount card, but usually not both on the same fill.

What pharmacies pay

The average U.S. drugstores pay for each strength (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

StrengthTri-Luma
creamper 30 g tube$235

Good to know