Trintellix savings card: $299 a month without insurance

How to pay the least

Lowest posted price

$299 a month

Trintellix from Takeda, without insurance.

Free from the maker, if you qualify Takeda Help at Hand. Have a household income equal to or less than 5 times the Federal Poverty Level Or call 1-800-830-9159.

See if you qualify

No generic is sold yet.

Compare every option

Brand nameTrintellix

Authorized genericvortioxetine

Regular genericvortioxetine

What you’d pay

Cash price$299a month with the maker’s card

Not soldThere isn’t one

Not soldNone sold yet

Same as Trintellix?

The original

–

Brand nameThe maker’s card

TRINTELLIX Savings Card

Savings card from Takeda

No insurance $299 a month

Insurance · as little as $10 a prescription

The card takes up to $100 a month off your co-pay.

Or call 1-866-279-0287.

In the maker’s words

“With the TRINTELLIX Savings Card, eligible, commercially-insured patients may pay as little as $10 for a 30- or 90-day prescription.”

“Pay $299 for a 30-day prescription.”

From the maker’s offer on us.trintellix.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s price above. You can usually use one or the other on a fill, not both.

Brand nameWith a free discount coupon

Optum Perks, Optum’s free discount coupon, lists these prices for Trintellix without insurance. Show the coupon from its page at the pharmacy; it can’t be used with insurance.

From Optum Perks, read November 2, 2026, with no location set. Its page opens on this dose; other doses and pharmacies near you are priced there too. With insurance, check your co-pay first: it may be lower.

Authorized genericNot sold

There isn’t one. An authorized generic is Trintellix itself, from the same company, sold without the brand name, and usually for less. For now Trintellix is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

No generic is sold yet. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

Depression

What the FDA label says

TRINTELLIX is indicated for the treatment of major depressive disorder (MDD) in adults.

Source: the FDA label for Trintellix (Takeda Pharmaceuticals America, Inc.), March 5, 2025. Full label on DailyMed

Good to know

“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/trintellix/