How do you pay?

How to pay the least

Ask for the cash price

Tybost

We didn’t find one.

  1. Ask your pharmacy for Tybost’s cash price, and one or two other pharmacies too.
  2. Tybost’s savings card works only with insurance from a job or one you bought.

Compare every option

Question
Brand nameTybost
Authorized genericcobicistat
Regular genericcobicistat
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldNone found
Same as Tybost?
The original
–
–

Brand nameThe maker’s card

Gilead Advancing Access Co-pay Savings Program

Savings card from Gilead Sciences

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a month

Sign up on gilead.com 

Or call 1-866-664-5327.

In the maker’s words

“Eligible patients could pay as little as $0 per month.”

From the maker’s offer on gilead.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Tybost itself, from the same company, sold without the brand name, and usually for less. For now Tybost is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

We didn’t find one. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

TYBOST is a CYP3A inhibitor indicated to increase systemic exposure of atazanavir or darunavir (once daily dosing regimen) in combination with other antiretroviral agents in the treatment of HIV-1 infection in adults and in pediatric patients weighing at least 14 kg.

Limitations of Use:

  • TYBOST is not interchangeable with ritonavir to increase systemic exposure of darunavir 600 mg twice daily, fosamprenavir, saquinavir, or tipranavir due to lack of exposure data. The use of TYBOST is not recommended with darunavir 600 mg twice daily, fosamprenavir, saquinavir, or tipranavir.
  • Complex or unknown mechanisms of drug interactions preclude extrapolation of ritonavir drug interactions to certain TYBOST interactions. TYBOST and ritonavir when administered with either atazanavir or darunavir may result in different drug interactions when used with concomitant medications.

Source: the FDA label for Tybost (Gilead Sciences, Inc.), February 10, 2026. Full label on DailyMed 

Good to know