Tykerb

Generic name: lapatinib

Used for: HER2-positive breast cancer

How do you pay?

How to pay the least

Lowest price

$1,443.30 for 30 tablets

Generic lapatinib 250 mg from Amazon Pharmacy, by mail

  1. Make a free account on pharmacy.amazon.com. Ask your prescriber to send the prescription there, or Amazon Pharmacy can transfer it.Open Amazon Pharmacy 
  2. Order generic lapatinib 250 mg. It comes by mail.

A regular generic has the same active ingredient as Tykerb, and the FDA requires it to work the same way.

Compare every option

Question
Brand nameTykerb
Authorized genericlapatinib
Regular genericlapatinib
What you’d pay
Cash priceAsk the pharmacyUsually the highest price
Not soldThere isn’t one
Lowest$1,443.30for 30 tablets at Amazon Pharmacy
Same as Tykerb?
The original
–
Same active ingredientFillers and dyes can differ

Brand nameThe maker’s card

Novartis Oncology Universal Co-pay Program

Savings card from Novartis

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $25 a prescription

The card takes up to $15,000 a year off your co-pay.

Sign up on copay.novartisoncology.com 

Or call 1-877-577-7756.

In the maker’s words

“Patients are responsible for up to the first $25 (specific offer varies by brand) and Novartis pays up to $15,000 per calendar year.”

From the maker’s offer on copay.novartisoncology.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Tykerb itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.

See the regular generic →

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic lapatinib, lowest first.

Delivered

From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericMakers and their savings cards

2 companies sell a generic of Tykerb that the FDA rates a substitute. A pharmacy fills whichever one it stocks. 2 of them have their own savings cards, listed first. Each works only with that maker’s version. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

It’s mostly filled by specialty pharmacies. Your prescriber’s office or insurer can tell you which one to use.

  • Lupin Pharmaceuticals250 mg

    Has a dye: FD&C Yellow No. 6 · Made by Natco Pharma

    Lupin Co-pay Savings Card: Lapatinib Tablets (generic Tykerb)

    With commercial insurance as little as $25

    Sign up on lupin.com

    In the maker’s words

    “A commercially insured patient with plan coverage for lapatinib may pay as little as $25.”

    How it looks, what’s in it, NDCs

    250 mg Orange, oval, 19 mm, marked “NTL”

    PackageNDC
    Bottle of 15068180-801-36

    Inactive ingredients: microcrystalline cellulose 101, FD&C Yellow No. 6, hypromellose, lecithin, soybean, magnesium stearate, polyethylene glycol 400, polysorbate 80, polyvinyl alcohol, povidone k30, sodium starch glycolate type a, talc, titanium dioxide, xanthan gum

    FDA label

  • Teva Pharmaceuticals250 mg

    Teva Lapatinib Tablets savings card

    With commercial insurance as little as $15

    Print the card (PDF)

    Or call 1-844-248-7949. See the offer on tevausa.com

    In the maker’s words

    “Commercially insured patients may pay as little as $15 out of pocket for Teva's Lapatinib Tablets.”

    Product page on tevausa.com

    How it looks, what’s in it, NDCs

    250 mg Yellow, oval, 19 mm, marked “L250 / TV”

    PackageNDC
    Bottle of 1500480-3237-51

    Inactive ingredients: ferric oxide yellow, magnesium stearate, cellulose, microcrystalline, polyethylene glycol 3350, polyvinyl alcohol, povidone k30, povidone k25, sodium starch glycolate type a potato, talc, titanium dioxide

    FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

What to say at the pharmacy

“Before you fill my Tykerb, can you tell me what I’d pay for the brand and for a generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

What it’s used for

What the FDA label says

TYKERB is a kinase inhibitor indicated in combination with:

  • capecitabine for the treatment of patients with advanced or metastatic breast cancer whose tumors overexpress human epidermal growth factor receptor 2 (HER2) and who have received prior therapy, including an anthracycline, a taxane, and trastuzumab. Limitations of Use: Patients should have disease progression on trastuzumab prior to initiation of treatment with TYKERB in combination with capecitabine.
  • letrozole for the treatment of postmenopausal women with hormone receptor-positive metastatic breast cancer that overexpresses the HER2 receptor for whom hormonal therapy is indicated.

TYKERB in combination with an aromatase inhibitor has not been compared to a trastuzumab-containing chemotherapy regimen for the treatment of metastatic breast cancer.

Source: the FDA label for Tykerb (Novartis Pharmaceuticals Corporation), January 27, 2026. Full label on DailyMed 

Good to know

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/tykerb/