Tyruko is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

How do you pay?

How to pay the least

Given by your care team

Billed by the clinic

Tyruko is given by a doctor or nurse, not picked up at a pharmacy.

  1. Ask your care team or your plan what you’d pay before your visit.

Compare every option

Question
Brand nameTyruko
Authorized genericnatalizumab-sztn
Regular genericnatalizumab-sztn
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldAsk the pharmacy
Same as Tyruko?
The original
–
–

Brand nameThe maker’s card

Sandoz One Source Co-Pay Program for TYRUKO

Savings card from Sandoz

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a treatment

Sign up on tyruko.com 

Or call 1-855-489-7856.

In the maker’s words

“Eligible, commercially insured patients may pay as little as $0 per TYRUKO treatment.”

From the maker’s offer on tyruko.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericNot sold

There isn’t one. An authorized generic is Tyruko itself, from the same company, sold without the brand name, and usually for less. For now Tyruko is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Tyruko is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

TYRUKO is an integrin receptor antagonist indicated for treatment of:

Multiple Sclerosis (MS)

TYRUKO is indicated as monotherapy for the treatment of relapsing forms of multiple sclerosis, to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults. Natalizumab products increase the risk of PML. When initiating and continuing treatment with TYRUKO, physicians should consider whether the expected benefit of TYRUKO is sufficient to offset this risk.

Crohn's Disease (CD)

  • TYRUKO is indicated for inducing and maintaining clinical response and remission in adult patients with moderately to severely active Crohn's disease with evidence of inflammation who have had an inadequate response to, or are unable to tolerate, conventional CD therapies and inhibitors of TNF-α.

Important Limitations:

  • In CD, TYRUKO should not be used in combination with immunosuppressants or inhibitors of TNF-α.

Source: the FDA label for Tyruko (Sandoz Inc), October 31, 2025. Full label on DailyMed 

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