Ultomiris is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

How do you pay?

How to pay the least

Given by your care team

Billed by the clinic

Ultomiris is given by a doctor or nurse, not picked up at a pharmacy.

  1. Ask your care team or your plan what you’d pay before your visit.

Compare every option

Question
Brand nameUltomiris
Authorized genericravulizumab
Regular genericravulizumab
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldAsk the pharmacy
Same as Ultomiris?
The original
–
–

Brand nameThe maker’s card

Alexion OneSource CoPay Program

Savings card from Alexion (AstraZeneca Rare Disease)

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0

Sign up on ultomiris.com 

Or call 1-888-765-4747.

In the maker’s words

“Pay as low as $0 in out-of-pocket costs…”

From the maker’s offer on ultomiris.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericNot sold

There isn’t one. An authorized generic is Ultomiris itself, from the same company, sold without the brand name, and usually for less. For now Ultomiris is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Ultomiris is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

ULTOMIRIS is a complement inhibitor indicated for:

  • the treatment of adult and pediatric patients one month of age and older with paroxysmal nocturnal hemoglobinuria (PNH).
  • the treatment of adult and pediatric patients one month of age and older with atypical hemolytic uremic syndrome (aHUS) to inhibit complement-mediated thrombotic microangiopathy (TMA). Limitations of Use: ULTOMIRIS is not indicated for the treatment of patients with Shiga toxin E. coli related hemolytic uremic syndrome (STEC-HUS).
  • the treatment of adult patients with generalized myasthenia gravis (gMG) who are anti-acetylcholine receptor (AChR) antibody-positive.
  • the treatment of adult patients with neuromyelitis optica spectrum disorder (NMOSD) who are anti-aquaporin-4 (AQP4) antibody-positive.

Source: the FDA label for Ultomiris (Alexion Pharmaceuticals Inc.), October 9, 2025. Full label on DailyMed 

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