Uplizna is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

How do you pay?

How to pay the least

Given by your care team

Billed by the clinic

Uplizna is given by a doctor or nurse, not picked up at a pharmacy.

  1. Ask your care team or your plan what you’d pay before your visit.

Compare every option

Question
Brand nameUplizna
Authorized genericinebilizumab
Regular genericinebilizumab
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldAsk the pharmacy
Same as Uplizna?
The original
–
–

Brand nameThe maker’s card

Amgen Commercial Co-Pay Program (Amgen By Your Side)

Savings card from Amgen (Horizon)

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a dose

Sign up on uplizna.com 

See the offer on uplizna.com

In the maker’s words

“YOU MAY PAY AS LITTLE AS $0 PER DOSE OF UPLIZNA…”

From the maker’s offer on uplizna.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericNot sold

There isn’t one. An authorized generic is Uplizna itself, from the same company, sold without the brand name, and usually for less. For now Uplizna is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Uplizna is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

UPLIZNA is a CD19-directed cytolytic antibody indicated for the treatment of:

  • Neuromyelitis optica spectrum disorder (NMOSD) in adult patients who are anti-aquaporin-4 (AQP4) antibody positive.
  • Immunoglobulin G4-related disease (IgG4-RD) in adult patients.
  • Generalized myasthenia gravis (gMG) in adult patients who are anti-acetylcholine receptor (AChR) or anti-muscle specific tyrosine kinase (MuSK) antibody positive.

Source: the FDA label for Uplizna (Horizon Therapeutics USA, Inc.), September 21, 2026. Full label on DailyMed 

Good to know