Brand-name prescription
Vagifem
estradiol
Compare your options
| Compare | VagifemBrand name | Authorized genericWithout the Vagifem name | Regular genericestradiol |
|---|---|---|---|
| What pharmacies pay | $20.32per insert | Not sold | Lowest$5.52per insert |
| Same as Vagifem? | The original | – | Same active ingredientFillers and dyes can differ |
| Ways to save | No maker card | – | Ask for it by name |
| With insurance | Brand co-pay, usually the highest | – | Usually the lowest co-pay |
No authorized generic: There isn’t one.
Prices are the average U.S. drugstores pay (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.
What pharmacies pay
The average U.S. drugstores pay for each strength (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.
| Strength | Vagifem | Regular generic |
|---|---|---|
| 10 mcg vaginal tabletper insert | $20.32 | $5.52 |
Good to know
- A regular generic has the same active ingredient, strength and form as Vagifem, and the FDA requires it to work the same way. Its fillers and dyes can differ, so it may look different.
- There’s no authorized generic of Vagifem.
- We didn’t find a savings card from Vagifem’s maker.
- Don’t stop or change a medicine without talking to your pharmacist or prescriber.