How do you pay?

How to pay the least

Ask for the cash price

Generic estradiol

No pharmacy we check posts a price for it.

  1. Ask your pharmacy for the cash price of generic estradiol.Find pharmacies near you 
  2. Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as Vivelle-Dot, and the FDA requires it to work the same way.

Compare every option

Question
Brand nameVivelle-Dot
Authorized genericestradiol
Regular genericestradiol
What you’d pay
Cash priceAsk the pharmacyUsually the highest price
Cash priceAsk the pharmacyUsually among the lowest
Cash priceAsk the pharmacyUsually among the lowest
Same as Vivelle-Dot?
The original
Same medicine
Same active ingredientFillers and dyes can differ

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Vivelle-Dot’s maker. Ask the pharmacy for Vivelle-Dot’s cash price. With insurance, ask what your plan charges.

Authorized genericThe NDC to ask for

The same medicine as Vivelle-Dot, without the brand name. Give the pharmacy its NDC to get it.

estradiol

Sold by
  • SandozThe company behind Vivelle-Dot
Your strength
NDC to ask for
  • 0.025 mg/daypatch
    • 0781-7129-8311-digit: 00781-7129-838 patches
  • 0.0375 mg/daypatch
    • 0781-7138-8311-digit: 00781-7138-838 patches
  • 0.05 mg/daypatch
    • 0781-7144-8311-digit: 00781-7144-838 patches
  • 0.075 mg/daypatch
    • 0781-7156-8311-digit: 00781-7156-838 patches
  • 0.1 mg/daypatch
    • 0781-7167-8311-digit: 00781-7167-838 patches

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Vivelle-Dot, can you tell me what I’d pay for the brand, for the authorized generic from Sandoz, and for a regular generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

0.025 mg/day patch

Same active and inactive ingredients as Vivelle-Dot.

BrandVivelle-Dot
Authorized genericSandoz
See the ingredients

Active: estradiol 0.025 mg/day

Inactive, on both labels:

  • Dipropylene glycol
  • Oleyl alcohol
  • Povidone

0.0375 mg/day patch

Same active and inactive ingredients as Vivelle-Dot.

BrandVivelle-Dot
Authorized genericSandoz
See the ingredients

Active: estradiol 0.0375 mg/day

Inactive, on both labels:

  • Dipropylene glycol
  • Oleyl alcohol
  • Povidone

0.05 mg/day patch

Same active and inactive ingredients as Vivelle-Dot.

BrandVivelle-Dot
Authorized genericSandoz
See the ingredients

Active: estradiol 0.05 mg/day

Inactive, on both labels:

  • Dipropylene glycol
  • Oleyl alcohol
  • Povidone

0.075 mg/day patch

Same active and inactive ingredients as Vivelle-Dot.

BrandVivelle-Dot
Authorized genericSandoz
See the ingredients

Active: estradiol 0.075 mg/day

Inactive, on both labels:

  • Dipropylene glycol
  • Oleyl alcohol
  • Povidone

0.1 mg/day patch

Same active and inactive ingredients as Vivelle-Dot.

BrandVivelle-Dot
Authorized genericSandoz
See the ingredients

Active: estradiol 0.1 mg/day

Inactive, on both labels:

  • Dipropylene glycol
  • Oleyl alcohol
  • Povidone

Regular genericWho makes it

3 companies sell a generic of Vivelle-Dot that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • Amneal PharmaceuticalsER patch 0.025 mg/day, 0.0375 mg/day, 0.05 mg/day, 0.075 mg/day, 0.1 mg/day

    Sold as Dotti

    How it looks, what’s in it, NDCs

    0.025 mg/day Round

    PackageNDC
    Carton of 865162-989-08

    0.0375 mg/day Round

    PackageNDC
    Carton of 865162-992-08

    0.05 mg/day Round

    PackageNDC
    Carton of 865162-993-08

    0.075 mg/day Round

    PackageNDC
    Carton of 865162-995-08

    0.1 mg/day Round

    PackageNDC
    Carton of 865162-997-08

    Inactive ingredients: dimethiconol/trimethylsiloxysilicate crosspolymer (40/60 w/w; 1000000 pa.s), oleyl alcohol, povidone, dipropylene glycol

    FDA label

  • Mylan PharmaceuticalsPatch 0.025 mg/day, 0.0375 mg/day, 0.05 mg/day, 0.075 mg/day, 0.1 mg/day

    Product page on viatris.com

    How it looks, what’s in it, NDCs

    0.025 mg/day

    PackageNDC
    Carton of 280378-4644-26

    0.0375 mg/day

    PackageNDC
    Carton of 280378-4643-26

    0.05 mg/day

    PackageNDC
    Carton of 280378-4642-26

    0.075 mg/day

    PackageNDC
    Carton of 280378-4641-26

    0.1 mg/day

    PackageNDC
    Carton of 280378-4640-26

    Inactive ingredients: dipropylene glycol, povidone, oleyl alcohol

    FDA label

  • Zydus LifesciencesER patch 0.025 mg/day, 0.0375 mg/day, 0.05 mg/day, 0.075 mg/day, 0.1 mg/day
    How it looks, what’s in it, NDCs

    0.025 mg/day

    PackageNDC
    Box of 2870710-1191-8

    0.0375 mg/day

    PackageNDC
    Box of 2870710-1192-8

    0.05 mg/day

    PackageNDC
    Box of 2870710-1193-8

    0.075 mg/day

    PackageNDC
    Box of 2870710-1194-8

    0.1 mg/day

    PackageNDC
    Box of 2870710-1195-8

    Inactive ingredients: oleic acid, povidone, propylene glycol, silicon dioxide

    FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

What the FDA label says

Vivelle-Dot is an estrogen indicated for:

  • Treatment of moderate to severe vasomotor symptoms due to menopause
  • Treatment of moderate to severe symptoms of vulvar and vaginal atrophy due to menopause

Limitations of Use When prescribing solely for the treatment of moderate to severe vaginal atrophy, first consider the use of topical vaginal products.

  • Treatment of hypoestrogenism due to hypogonadism, castration, or primary ovarian failure
  • Prevention of postmenopausal osteoporosis

Limitations of Use When prescribing solely for the prevention of postmenopausal osteoporosis, first consider the use of non-estrogen medications. Consider estrogen therapy only for women at significant risk of osteoporosis.

Source: the FDA label for Vivelle-Dot (Sandoz Inc), November 17, 2023. Full label on DailyMed 

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