Vyleesi Copay Assistance (Cosette)
With commercial insurance
$0 for a 4-dose box
Paying cash, no insurance
$99 for a 4-dose box
“Most commercially insured patients pay $0 for a 4-dose box of Vyleesi.”
“If you don’t have insurance coverage for Vyleesi, a 4-dose box is available for just $99.”
From the maker’s offer on vyleesi.com, checked September 25, 2026. What you pay depends on your plan. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.