How do you pay?

How to pay the least

Lowest posted price

$99 for a 4-dose box

Vyleesi from Cosette Pharmaceuticals, without insurance.

  1. Sign up for Vyleesi Copay Assistance (Cosette). Or call 1-833-799-5028.Sign up on vyleesi.com 

We didn’t find one.

Compare every option

Question
Brand nameVyleesi
Authorized genericbremelanotide
Regular genericbremelanotide
What you’d pay
Cash price$99for a 4-dose box with the maker’s card
Not soldThere isn’t one
Not soldNone found
Same as Vyleesi?
The original
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–

Brand nameThe maker’s card

Vyleesi Copay Assistance (Cosette)

Savings card from Cosette Pharmaceuticals

No insurance $99 for a 4-dose box
Insurance $0 for a 4-dose box

Sign up on vyleesi.com 

Or call 1-833-799-5028.

In the maker’s words

“Most commercially insured patients pay $0 for a 4-dose box of Vyleesi.”

“If you don’t have insurance coverage for Vyleesi, a 4-dose box is available for just $99.”

From the maker’s offer on vyleesi.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s price above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Vyleesi itself, from the same company, sold without the brand name, and usually for less. For now Vyleesi is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

We didn’t find one. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

VYLEESI is a melanocortin receptor agonist indicated for the treatment of premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD) as characterized by low sexual desire that causes marked distress or interpersonal difficulty and is NOT due to:

  • A co-existing medical or psychiatric condition,
  • Problems with the relationship, or
  • The effects of a medication or drug substance.

Limitations of Use:

  • Not indicated for treatment of HSDD in postmenopausal women or in men.
  • Not indicated to enhance sexual performance.

Source: the FDA label for Vyleesi (Cosette Pharmaceuticals, Inc.), November 13, 2025. Full label on DailyMed 

Good to know