How do you pay?

How to pay the least

Ask for the cash price

Xatmep

Sold only in a different form, strength or formula. Switching to one would need a new prescription, so ask your prescriber whether it could work for you.

  1. Ask your pharmacy for Xatmep’s cash price, and one or two other pharmacies too.
  2. Xatmep’s savings card works only with insurance from a job or one you bought.

Free from the maker, if you qualify Azurity Solutions Patient Assistance Program. Patient must meet the eligibility and income requirements to qualify for the program. Or call 1-844-472-2032.

See if you qualify 

Compare every option

Question
Brand nameXatmep
Authorized genericmethotrexate
Regular genericmethotrexate
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Other forms onlyAsk your doctor
Same as Xatmep?
The original
–
–

Brand nameThe maker’s card

Xatmep Co-Pay Assistance (Azurity Solutions)

Savings card from Azurity Pharmaceuticals

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $5 a fill

Sign up on xatmep.azuritysolutions.com 

Or call 1-800-388-2316.

In the maker’s words

“Commercially insured patients may pay as little as $5.”

From the maker’s offer on xatmep.azuritysolutions.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Xatmep itself, from the same company, sold without the brand name, and usually for less. For now Xatmep is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Sold only in a different form, strength or formula. Switching to one would need a new prescription, so ask your prescriber whether it could work for you. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

XATMEP is a folate analog metabolic inhibitor indicated for the:

  • Treatment of pediatric patients with acute lymphoblastic leukemia (ALL) as a component of a combination chemotherapy maintenance regimen.
  • Management of pediatric patients with active polyarticular juvenile idiopathic arthritis (pJIA) who are intolerant of or had an inadequate response to first-line therapy.

Source: the FDA label for Xatmep (Azurity Pharmaceuticals, Inc.), May 28, 2026. Full label on DailyMed 

Good to know