Xenpozyme savings card from the maker

Xenpozyme is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

How to pay the least

Given by your care team

Billed by the clinic

Xenpozyme is given by a doctor or nurse, not picked up at a pharmacy.

Ask your care team or your plan what you’d pay before your visit.

Compare every option

Brand nameXenpozyme

Authorized genericolipudase alfa-rpcp

Regular genericolipudase alfa-rpcp

What you’d pay

Cash priceAsk the pharmacy

Not soldThere isn’t one

Not soldAsk the pharmacy

Same as Xenpozyme?

The original

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Brand nameThe maker’s card

CareConnect Copay Program

Savings card from Sanofi

Xenpozyme’s maker has a savings program. Its page doesn’t list a dollar amount.

Or call 1-800-745-4447. See the offer on xenpozyme.com

From the maker’s site, checked November 2, 2026. Check the maker’s page for who can use it.

Authorized genericNot sold

There isn’t one. An authorized generic is Xenpozyme itself, from the same company, sold without the brand name, and usually for less. For now Xenpozyme is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Xenpozyme is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

Acid sphingomyelinase deficiency (ASMD)

What the FDA label says

XENPOZYME is a hydrolytic lysosomal sphingomyelin-specific enzyme indicated for treatment of non–central nervous system manifestations of acid sphingomyelinase deficiency (ASMD) in adult and pediatric patients.

Source: the FDA label for Xenpozyme (Genzyme Corporation), December 11, 2025. Full label on DailyMed

Good to know

“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Check the maker’s page for who can use it.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to the clinic’s billing office.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/xenpozyme/