How do you pay?

How to pay the least

Ask for the cash price

Xermelo

We didn’t find one.

  1. Ask your pharmacy for Xermelo’s cash price, and one or two other pharmacies too.
  2. Xermelo’s savings card works only with insurance from a job or one you bought.

Compare every option

Question
Brand nameXermelo
Authorized generictelotristat ethyl
Regular generictelotristat ethyl
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldNone found
Same as Xermelo?
The original
–
–

Brand nameThe maker’s card

XERMELO Co-pay Savings Program

Savings card from TerSera Therapeutics

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a fill

Sign up on copay.xermelo.com 

Or call 1-844-937-6356.

In the maker’s words

“XERMELO patients may pay as little as $0 out-of-pocket for each prescription fill, dose, or cycle of XERMELO.”

From the maker’s offer on copay.xermelo.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Xermelo itself, from the same company, sold without the brand name, and usually for less. For now Xermelo is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

We didn’t find one. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

Xermelo is a tryptophan hydroxylase inhibitor indicated for the treatment of carcinoid syndrome diarrhea in combination with somatostatin analog (SSA) therapy in adults inadequately controlled by SSA therapy.

Source: the FDA label for Xermelo (TerSera Therapeutics LLC), August 6, 2026. Full label on DailyMed 

Good to know