How do you pay?

How to pay the least

Ask for the cash price

Xgeva

Xgeva is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

  1. Ask your pharmacy for Xgeva’s cash price, and one or two other pharmacies too.
  2. Xgeva’s savings card works only with insurance from a job or one you bought.

Compare every option

Question
Brand nameXgeva
Authorized genericdenosumab
Regular genericdenosumab
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldNone sold yet
Same as Xgeva?
The original
–
–

Brand nameThe maker’s card

Amgen SupportPlus Co-Pay Program

Savings card from Amgen

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a dose

Sign up on xgeva.com 

Or call 1-866-264-2778.

In the maker’s words

“Pay as little as $0 out-of-pocket for each dose…”

From the maker’s offer on xgeva.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Xgeva itself, from the same company, sold without the brand name, and usually for less. For now Xgeva is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Xgeva is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

Xgeva is a RANK ligand (RANKL) inhibitor indicated for:

  • Prevention of skeletal-related events in patients with multiple myeloma and in patients with bone metastases from solid tumors.
  • Treatment of adults and skeletally mature adolescents with giant cell tumor of bone that is unresectable or where surgical resection is likely to result in severe morbidity.
  • Treatment of hypercalcemia of malignancy refractory to bisphosphonate therapy.

Source: the FDA label for Xgeva (Amgen, Inc), June 23, 2026. Full label on DailyMed 

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