Brand-name prescription

Xhance

fluticasone

Compare your options

Compare	XhanceBrand name	Authorized genericWithout the Xhance name	Regular genericfluticasone
What pharmacies pay	$40.84per mL	Not sold	Other forms only
Same as Xhance?	The original	–	–
Ways to save	Maker’s cardas little as $0 a prescriptionwith commercial insurance	–	–
With insurance	Your plan’s brand co-pay	–	–

No authorized generic: There isn’t one.

Regular generic: Sold only in a different form, strength or formula. Switching to one would need a new prescription, so ask your prescriber whether it could work for you.

Prices are the average U.S. drugstores pay (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

The maker’s savings card

Rx Maker’s savings card OptiNose

XHANCE Copay Program

With commercial insurance

as little as $0 a prescription

No insurance

This card needs commercial insurance. The maker doesn’t list a cash price on this page.

Get it on xhancehcp.com

In the maker’s words

“Eligible, commercially insured patients with coverage for XHANCE pay as little as $0 using the XHANCE copay card…”

From the maker’s offer on xhancehcp.com, checked September 25, 2026. What you pay depends on your plan. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Before you use a discount card

Discount cards like GoodRx take money off the pharmacy’s cash price. For a brand-name drug, that price is often still high. With commercial insurance, Xhance’s own card may bring it to as little as $0 a prescription.

Look up the discount-card price, then compare it with this estimate. You can use a maker’s card or a discount card, but usually not both on the same fill.

What pharmacies pay

The average U.S. drugstores pay for each strength (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Strength	Xhance
93 mcg exhalation delivery nasal sprayper mL	$40.84

Good to know

There’s no authorized generic of Xhance.
“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.