Xhance savings card: as little as $0 a prescription with commercial insurance

How to pay the least

Ask for the cash price

Xhance

Sold only in a different form, strength or formula. Switching to one would need a new prescription, so ask your prescriber whether it could work for you.

Ask your pharmacy for Xhance’s cash price, and one or two other pharmacies too.
Xhance’s savings card works only with insurance from a job or one you bought.

Compare every option

Brand nameXhance

Authorized genericfluticasone

Regular genericfluticasone

What you’d pay

Cash priceAsk the pharmacy

Not soldThere isn’t one

Other forms onlyAsk your doctor

Same as Xhance?

The original

–

Brand nameThe maker’s card

XHANCE Copay Program

Savings card from OptiNose

No insuranceNeeds insuranceNo cash price listed.

Insurance · as little as $0 a prescription

In the maker’s words

“Eligible, commercially insured patients with coverage for XHANCE pay as little as $0 using the XHANCE copay card…”

From the maker’s offer on xhancehcp.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Xhance itself, from the same company, sold without the brand name, and usually for less. For now Xhance is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Sold only in a different form, strength or formula. Switching to one would need a new prescription, so ask your prescriber whether it could work for you. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

XHANCE is a corticosteroid indicated for the treatment of:

Chronic rhinosinusitis with nasal polyps (CRSwNP) in adults.
Chronic rhinosinusitis without nasal polyps (CRSsNP) in adults.

Source: the FDA label for Xhance (Paratek Pharmaceuticals, Inc.), May 19, 2026. Full label on DailyMed

Good to know

“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/xhance/