Xiaflex savings card: $0 a vial with commercial insurance

How to pay the least

Ask for the cash price

Xiaflex

Xiaflex is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

Ask your pharmacy for Xiaflex’s cash price, and one or two other pharmacies too.
Xiaflex’s savings card works only with insurance from a job or one you bought.

Compare every option

Brand nameXiaflex

Authorized genericcollagenase clostridium histolyticum

Regular genericcollagenase clostridium histolyticum

What you’d pay

Cash priceAsk the pharmacy

Not soldThere isn’t one

Not soldAsk the pharmacy

Same as Xiaflex?

The original

–

Brand nameThe maker’s card

XIAFLEX Copay Assistance Program (Zero Pay Program)

Savings card from Keenova Therapeutics (formerly Endo)

No insuranceNeeds insuranceNo cash price listed.

Insurance $0 a vial

Or call 1-844-343-4221.

In the maker’s words

“Most eligible patients with commercial insurance plans should pay a $0 copay for XIAFLEX.”

From the maker’s offer on peyronies-disease.xiaflex.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Xiaflex itself, from the same company, sold without the brand name, and usually for less. For now Xiaflex is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Xiaflex is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

XIAFLEX is a combination of bacterial collagenases indicated for the treatment of:

Adult patients with Dupuytren’s contracture with a palpable cord
Adult men with Peyronie’s disease with a palpable plaque and curvature deformity of at least 30 degrees at the start of therapy

Source: the FDA label for Xiaflex (Endo USA, Inc.), September 17, 2026. Full label on DailyMed

Good to know

“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/xiaflex/