Xifaxan savings card: as little as $0 a prescription with commercial insurance

How to pay the least

Ask for the cash price

Xifaxan

We didn’t find one.

Ask your pharmacy for Xifaxan’s cash price, and one or two other pharmacies too.
Xifaxan’s savings card works only with insurance from a job or one you bought.

Free from the maker, if you qualify Bausch Health Patient Assistance Program. Your total annual household income must not exceed 300% of the Federal Poverty Level (FPL) based on household size Or call 1-833-862-8727.

See if you qualify

Compare every option

Brand nameXifaxan

Authorized genericrifaximin

Regular genericrifaximin

What you’d pay

Cash priceAsk the pharmacy

Not soldThere isn’t one

Not soldNone found

Same as Xifaxan?

The original

–

Brand nameThe maker’s card

XIFAXAN Instant Copay Savings Card

Savings card from Salix Pharmaceuticals (Bausch Health)

No insuranceNeeds insuranceNo cash price listed.

Insurance · as little as $0 a prescription

Or text PAYZERO to 69970, or call 1-866-943-2926.

In the maker’s words

“With the XIFAXAN Savings Card, most eligible patients with commercial insurance and coverage for XIFAXAN may pay as little as $0 for their XIFAXAN prescription.”

From the maker’s offer on xifaxan.copaysavingsprogram.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Xifaxan itself, from the same company, sold without the brand name, and usually for less. For now Xifaxan is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

We didn’t find one. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

XIFAXAN is a rifamycin antibacterial indicated for:

Treatment of travelers’ diarrhea (TD) caused by noninvasive strains of Escherichia coli in adult and pediatric patients 12 years of age and older.
Reduction in risk of overt hepatic encephalopathy (HE) recurrence in adults.
Treatment of irritable bowel syndrome with diarrhea (IBS-D) in adults.

Limitations of Use TD: Should not use in patients with diarrhea complicated by fever or blood in the stool or diarrhea due to pathogens other than Escherichia coli.

Source: the FDA label for Xifaxan (Salix Pharmaceuticals, Inc.), June 25, 2025. Full label on DailyMed

Good to know

“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/xifaxan/