Xigduo XR

Generic name: dapagliflozin and metformin

Used for: Type 2 diabetes · Heart failure · Keeping chronic kidney disease from getting worse · Lowering the risk of a hospital stay for heart failure · 3 more

How do you pay?

How to pay the least

From

$23.46 for 30 tablets delivered ($18.21 plus $5.25 shipping)

Generic dapagliflozin and metformin XR from Cost Plus Drugs, by mail. Pick the strength on your label above for its own price.

  1. Make a free account on costplusdrugs.com. Ask your prescriber to send the prescription there, or Cost Plus Drugs can transfer it.Open Cost Plus Drugs 
  2. Order generic dapagliflozin and metformin XR. It comes by mail.

With a membership From $14.91 for 30 tablets from Amazon Pharmacy, by mail ($139 a year).

Open Amazon Pharmacy 

Has to be Xigduo XR? AstraZeneca sells it for $45 for 60 tablets without insurance.

Sign up on azpatientdirect.com 

A regular generic has the same active ingredient as Xigduo XR, and the FDA requires it to work the same way.

Compare every option

Question
Brand nameXigduo XR
Authorized genericdapagliflozin and metformin
Regular genericdapagliflozin and metformin
What you’d pay
Cash price$45for 60 tablets from the maker
Cash priceAsk the pharmacyUsually the lowest
From$23.46for 30 tablets at Cost Plus Drugs, with shipping
Same as Xigduo XR?
The original
Same medicine
Same active ingredientFillers and dyes can differ

Brand nameThe maker’s card

Xigduo XR’s maker has a savings card that lowers what you pay at the pharmacy.

FARXIGA or XIGDUO XR Savings Card

Savings card from AstraZeneca

No insurance $45 for 60 tablets, from AstraZeneca Direct
Insurance · as little as $0

Print the card (PDF) 

Or call 1-844-292-4682. See the offer on azpatientsupport.com

In the maker’s words

“Pay as little as $0 for XIGDUO XR for eligible Commercially Insured patients…”

“XIGDUO XR may be available for direct purchase to eligible patients $45.00 per 60 tablets…”

From the maker’s offer on azpatientsupport.com, checked October 27, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Brand nameTrumpRx.gov price

TrumpRx.gov, the federal government’s drug price site, lists Xigduo XR at a price its maker agreed to, for people paying without insurance.

  • TrumpRx.gov $45for 30 tabletsSame price for 2.5/1000 mg, 5/500 mg, 5/1000 mg, 10/500 mg and 10/1000 mgTrumpRx sends you to AstraZeneca Direct, AstraZeneca’s own program, to order it.

From TrumpRx.gov, read October 28, 2026. Its page opens on this price; other strengths and amounts are priced there too. With insurance, check your co-pay first: it may be lower.

Authorized genericThe NDC to ask for

The same medicine as Xigduo XR, without the brand name. Give the pharmacy its NDC to get it.

dapagliflozin and metformin

Sold by
  • Prasco Laboratories
Your strength
NDC to ask for
  • 5 mg / 1,000 mgextended-release tablet
    • 66993-361-6011-digit: 66993-0361-6060 tablets per bottle
  • 10 mg / 1,000 mgextended-release tablet
    • 66993-362-3011-digit: 66993-0362-3030 tablets per bottle

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Xigduo XR, can you tell me what I’d pay for the brand, for the authorized generic from Prasco Laboratories, and for a regular generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

5 mg / 1,000 mg extended-release tablet

Same active and inactive ingredients as Xigduo XR.

BrandXigduo XR
Authorized genericPrasco Laboratories
See the ingredients

Active: dapagliflozin propanediol 5 mg · metformin hydrochloride 1,000 mg

Inactive, on both labels:

  • Anhydrous lactose
  • Carboxymethylcellulose sodium
  • Crospovidone
  • Hypromellose 2208
  • Hypromellose 2910
  • Magnesium stearate
  • Microcrystalline cellulose
  • Silicon dioxide

10 mg / 1,000 mg extended-release tablet

Same active and inactive ingredients as Xigduo XR.

BrandXigduo XR
Authorized genericPrasco Laboratories
See the ingredients

Active: dapagliflozin propanediol 10 mg · metformin hydrochloride 1,000 mg

Inactive, on both labels:

  • Anhydrous lactose
  • Carboxymethylcellulose sodium
  • Crospovidone
  • Hypromellose 2208
  • Magnesium stearate
  • Microcrystalline cellulose
  • Silicon dioxide

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic dapagliflozin and metformin, lowest first.

Delivered

From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericWho makes it

6 companies sell a generic of Xigduo XR that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • Ascend Laboratories5 mg / 1,000 mg, 5 mg / 500 mg, 10 mg / 1,000 mg, 10 mg / 500 mg

    Has lactose · Has a dye: FD&C Yellow No. 6 · Made by Alkem Laboratories

    How it looks, what’s in it, NDCs

    5 mg / 1,000 mg Pink to dark pink colored, oval, 20 mm, marked “D / M / 5 / 1000”

    PackageNDC
    Bottle of 3067877-620-30
    Bottle of 6067877-620-60
    Bottle of 9067877-620-90

    5 mg / 500 mg Orange, capsule, 20 mm, marked “D / M / 5 / 500”

    PackageNDC
    Bottle of 3067877-619-30
    Bottle of 50067877-619-05

    10 mg / 1,000 mg Yellow to dark yellow colored, oval, 20 mm, marked “D / M / 10 / 1000”

    PackageNDC
    Bottle of 3067877-622-30
    Bottle of 9067877-622-90
    Carton of 10067877-622-38
    Bottle of 40067877-622-40

    10 mg / 500 mg Pink to light pink colored, capsule, 20 mm, marked “D / M / 10 / 500”

    PackageNDC
    Bottle of 3067877-621-30
    Carton of 10067877-621-38
    Bottle of 50067877-621-05

    Inactive ingredients: lactose monohydrate, microcrystalline cellulose, low-substituted hydroxypropyl cellulose (11% hydroxypropyl; 130000 mw), hypromellose 2910 (3 mpa.s), silicon dioxide, magnesium stearate, copovidone, povidone k90, carboxymethylcellulose sodium, polyvinyl alcohol, talc, titanium dioxide, glyceryl monocaprylocaprate, sodium lauryl sulfate, ferric oxide red, FD&C Yellow No. 6, ferric oxide yellow

    FDA label

  • Aurobindo Pharma5 mg / 1,000 mg, 5 mg / 500 mg, 10 mg / 1,000 mg, 10 mg / 500 mg

    Has a dye: FD&C Yellow No. 6 aluminum lake

    How it looks, what’s in it, NDCs

    5 mg / 1,000 mg Pink to dark pink, oval, 20 mm, marked “N / 16”

    PackageNDC
    Bottle of 3059651-155-30
    Bottle of 6059651-155-60
    Bottle of 40059651-155-04

    5 mg / 500 mg Light orange to orange, oval, 20 mm, marked “N / 15”

    PackageNDC
    Bottle of 3059651-154-30
    Bottle of 50059651-154-05

    10 mg / 1,000 mg Yellow to dark yellow, oval, 20 mm, marked “N / 25”

    PackageNDC
    Bottle of 3059651-157-30
    Bottle of 40059651-157-04

    10 mg / 500 mg Light pink to pink, oval, 20 mm, marked “N / 19”

    PackageNDC
    Bottle of 3059651-156-30
    Bottle of 50059651-156-05

    Inactive ingredients: carboxymethylcellulose sodium, silicon dioxide, crospovidone (120 .mu.m), glyceryl mono- and dicaprylocaprate, hypromellose 2208 (100000 mpa.s), mannitol, microcrystalline cellulose, polyvinyl alcohol, sodium lauryl sulfate, sodium stearyl fumarate, talc, titanium dioxide, ferric oxide yellow, ferric oxide red, hypromellose 2910 (5 mpa.s), FD&C Yellow No. 6 aluminum lake

  • Lupin Pharmaceuticals5 mg / 1,000 mg, 5 mg / 500 mg, 10 mg / 1,000 mg, 10 mg / 500 mg
    Packages and NDCs

    5 mg / 1,000 mg

    PackageNDC
    Bottle of 6070748-102-07

    5 mg / 500 mg

    PackageNDC
    Bottle of 3070748-101-06

    10 mg / 1,000 mg

    PackageNDC
    Bottle of 3070748-104-06

    10 mg / 500 mg

    PackageNDC
    Bottle of 3070748-103-06
  • Macleods Pharmaceuticals5 mg / 1,000 mg, 5 mg / 500 mg, 10 mg / 1,000 mg, 10 mg / 500 mg
    Packages and NDCs

    5 mg / 1,000 mg

    PackageNDC
    Carton of 3033342-408-06
    Bottle of 3033342-408-07
    Bottle of 6033342-408-09
    Bottle of 9033342-408-10
    Bottle of 50033342-408-15

    5 mg / 500 mg

    PackageNDC
    Carton of 3033342-406-06
    Bottle of 3033342-406-07
    Bottle of 6033342-406-09
    Bottle of 9033342-406-10
    Bottle of 50033342-406-15

    10 mg / 1,000 mg

    PackageNDC
    Carton of 3033342-409-06
    Bottle of 3033342-409-07
    Bottle of 6033342-409-09
    Bottle of 9033342-409-10
    Bottle of 50033342-409-15

    10 mg / 500 mg

    PackageNDC
    Carton of 3033342-407-06
    Bottle of 3033342-407-07
    Bottle of 6033342-407-09
    Bottle of 9033342-407-10
    Bottle of 50033342-407-15
  • Novadoz Pharmaceuticals5 mg / 1,000 mg, 5 mg / 500 mg, 10 mg / 1,000 mg, 10 mg / 500 mg

    Has lactose · Made by MSN Laboratories

    Product page on novadozpharma.com

    How it looks, what’s in it, NDCs

    5 mg / 1,000 mg Light pink, oval, 20 mm, marked “MD5”

    PackageNDC
    Bottle of 3072205-435-01
    Bottle of 6072205-435-03
    Bottle of 40072205-435-02

    5 mg / 500 mg Light pink, capsule, 19 mm, marked “MD6”

    PackageNDC
    Bottle of 3072205-434-01
    Bottle of 50072205-434-02

    10 mg / 1,000 mg Brown, oval, 20 mm, marked “MD4”

    PackageNDC
    Bottle of 3072205-437-01
    Bottle of 6072205-437-03
    Bottle of 40072205-437-02

    10 mg / 500 mg Brown, capsule, 19 mm, marked “MD7”

    PackageNDC
    Bottle of 3072205-436-01
    Bottle of 50072205-436-02

    Inactive ingredients: polyvinyl alcohol, polyethylene glycol, talc, titanium dioxide, ferrosoferric oxide, carboxymethylcellulose sodium, crospovidone, hypromellose, ferric oxide red, lactose monohydrate, magnesium stearate, microcrystalline cellulose, silicon dioxide, sodium lauryl sulfate

    FDA label

  • Sun Pharmaceutical Industries5 mg / 1,000 mg, 10 mg / 1,000 mg, 10 mg / 500 mg
    Packages and NDCs

    5 mg / 1,000 mg

    PackageNDC
    Bottle of 3063304-026-30
    Bottle of 6063304-026-62
    Bottle of 40063304-026-54

    10 mg / 1,000 mg

    PackageNDC
    Bottle of 3063304-028-30
    Bottle of 40063304-028-54

    10 mg / 500 mg

    PackageNDC
    Bottle of 3063304-027-30
    Bottle of 40063304-027-54

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

What the FDA label says

XIGDUO XR is a combination of dapagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and metformin hydrochloride (HCl), a biguanide, indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients aged 10 years and older with type 2 diabetes mellitus.

Dapagliflozin when used as a component of XIGDUO XR, is indicated in adults with type 2 diabetes mellitus to reduce the risk of:

  • Sustained eGFR decline, end-stage kidney disease, cardiovascular (CV) death, and hospitalization for heart failure in patients with chronic kidney disease at risk of progression.
  • CV death, hospitalization for heart failure, and urgent heart failure visit in patients with heart failure.
  • Hospitalization for heart failure in patients with type 2 diabetes mellitus and either established CV disease or multiple CV risk factors.

Limitations of use:

  • Not recommended for use to improve glycemic control in patients with type 1 diabetes mellitus.
  • Because of the metformin HCl component, the use of XIGDUO XR is limited to patients with type 2 diabetes mellitus for all indications.
  • Not recommended for the treatment of chronic kidney disease in patients with polycystic kidney disease or patients requiring or with a recent history of immunosuppressive therapy for the treatment of kidney disease. XIGDUO XR is not expected to be effective in these populations.

Source: the FDA label for Xigduo XR (AstraZeneca Pharmaceuticals LP), August 11, 2026. Full label on DailyMed 

Good to know

Prices checked October 27, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/xigduo-xr/