Brand-name prescription

Xiidra

lifitegrast

Compare your options

Compare	XiidraBrand name	Authorized genericWithout the Xiidra name	Regular genericlifitegrast
What pharmacies pay	$11.83per ampule	Not sold	Not sold
Same as Xiidra?	The original	–	–
Ways to save	Maker’s cardas little as $0 a prescriptionwith commercial insurance	–	–
With insurance	Your plan’s brand co-pay	–	–

No authorized generic: There isn’t one.

No regular generic: No generic is sold yet.

Prices are the average U.S. drugstores pay (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

The maker’s savings card

Rx Maker’s savings card Bausch + Lomb

Xiidra My Saviings Program

With commercial insurance

as little as $0 a prescription

Paying cash, no insurance

from $225 a month

Get it on xiidra.blsavingscard.com

In the maker’s words

“may pay as little as $0 for their prescription of Xiidra.”

“fixed cash price of $225, $450, or $675 for each 30, 60, and…”

From the maker’s offer on xiidra.blsavingscard.com, checked September 25, 2026. What you pay depends on your plan. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Before you use a discount card

Discount cards like GoodRx take money off the pharmacy’s cash price. For a brand-name drug, that price is often still high. With commercial insurance, Xiidra’s own card may bring it to as little as $0 a prescription. Paying cash, the maker’s own price is from $225 a month.

Look up the discount-card price, then compare it with this estimate. You can use a maker’s card or a discount card, but usually not both on the same fill.

What pharmacies pay

The average U.S. drugstores pay for each strength (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Strength	Xiidra
5% eye dropsper ampule	$11.83

Good to know

There’s no authorized generic of Xiidra.
“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.