Xolair

Generic name: omalizumab

Used for: Moderate to severe allergic asthma · Chronic hives · Nasal polyps with chronic sinusitis · Food allergies (fewer reactions after accidental exposure) · 3 more

How do you pay?

How to pay the least

Ask for the cash price

Xolair

Xolair is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

  1. Ask your pharmacy for Xolair’s cash price, and one or two other pharmacies too.
  2. Xolair’s savings card works only with insurance from a job or one you bought.

Free from the maker, if you qualify Genentech Patient Foundation. Do not have insurance coverage for their Genentech medicine and their household makes less than $150,000 per year Or call (888) 941-3331.

See if you qualify 

Compare every option

Question
Brand nameXolair
Authorized genericomalizumab
Regular genericomalizumab
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldAsk the pharmacy
Same as Xolair?
The original
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–

Brand nameThe maker’s card

XOLAIR Co-pay Program

Savings card from Genentech

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0

The card takes up to $15,000 a year off your co-pay.

Sign up on xolair.com 

Or call 1-866-422-2377.

In the maker’s words

“With the XOLAIR Co-pay Program, eligible patients with commercial insurance may pay as little as $0 XOLAIR drug out-of-pocket cost.”

From the maker’s offer on xolair.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Xolair itself, from the same company, sold without the brand name, and usually for less. For now Xolair is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Xolair is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

XOLAIR is an anti-IgE antibody indicated for:

  • Moderate to severe persistent asthma in adults and pediatric patients 6 years of age and older with a positive skin test or in vitro reactivity to a perennial aeroallergen and symptoms that are inadequately controlled with inhaled corticosteroids
  • Chronic rhinosinusitis with nasal polyps (CRSwNP) in adult patients 18 years of age and older with inadequate response to nasal corticosteroids, as add-on maintenance treatment
  • IgE-mediated food allergy in adult and pediatric patients aged 1 year and older for the reduction of allergic reactions (Type I), including anaphylaxis, that may occur with accidental exposure to one or more foods. To be used in conjunction with food allergen avoidance
  • Chronic spontaneous urticaria (CSU) in adults and adolescents 12 years of age and older who remain symptomatic despite H1 antihistamine treatment

Limitations of Use:

  • Not indicated for acute bronchospasm or status asthmaticus.
  • Not indicated for the emergency treatment of allergic reactions, including anaphylaxis
  • Not indicated for other forms of urticaria.

Source: the FDA label for Xolair (Genentech, Inc.), August 13, 2026. Full label on DailyMed 

Good to know

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/xolair/