Xopenex HFA vs. its authorized generic and generics

How to pay the least

Lowest posted price

$40 a fill

Xopenex HFA from Lupin Pharmaceuticals, without insurance.

Ask about the authorized generic Xopenex HFA itself, without the brand name. Ask your pharmacy for its price; its NDC is on this page.

See its NDC

None is sold. The authorized generic is the only generic.

Compare every option

Brand nameXopenex HFA

Authorized genericlevalbuterol

Regular genericlevalbuterol

What you’d pay

Cash price$40a fill with the maker’s card

Cash priceAsk the pharmacyUsually the lowest

Not soldNone sold

Same as Xopenex HFA?

The original

Same medicine

–

Brand nameThe maker’s card

Xopenex HFA’s maker has a savings card that lowers what you pay at the pharmacy.

Xopenex HFA Savings Card

Savings card from Lupin Pharmaceuticals

No insurance $40 a fill

Insurance · as little as $25 a fill

In the maker’s words

“$25 for eligible commercially insured patients.”

“$40 for eligible Direct Access patients.”

From the maker’s offer on xopenexhfa.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericThe NDC to ask for

The same medicine as Xopenex HFA, without the brand name. Give the pharmacy its NDC to get it.

levalbuterol

Sold by

Actavis Pharma

NDC to ask for

45 mcginhaler
- 0591-2927-5411-digit: 00591-2927-54200 puffs per inhaler

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Xopenex HFA, can you tell me what I’d pay for the brand, for the authorized generic from Actavis Pharma (NDC 0591-2927-54)?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

Same active and inactive ingredients as Xopenex HFA.

Xopenex HFA package label — BrandXopenex HFA

Authorized generic package label from Actavis Pharma — Authorized genericActavis Pharma

See the ingredients

Active: levalbuterol tartrate 45 mcg

Inactive, on both labels:

Alcohol
Norflurane
Oleic acid

Regular genericNot sold

None is sold. The authorized generic is the only generic. Generics usually come once the brand’s patents and exclusivity end. Until then, the authorized generic is the lower-cost way to get Xopenex HFA.

See the authorized generic →

What it’s used for

Narrowed airways (bronchospasm)

What the FDA label says

XOPENEX HFA is a beta2-adrenergic agonist indicated for the treatment or prevention of bronchospasm in patients 4 years of age and older with reversible obstructive airway disease.

Source: the FDA label for Xopenex HFA (Lupin Pharmaceuticals, Inc.), June 2, 2025. Full label on DailyMed

Good to know

It may look different from Xopenex HFA (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Cash prices can differ a lot from one pharmacy to the next, so it can pay to ask two. With insurance, what you pay depends on your plan.
If your pharmacy doesn’t stock it, they can often order it within a day or two.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/xopenex-hfa/