Xyntha savings card: as little as $0 a fill with commercial insurance

How to pay the least

Ask for the cash price

Xyntha

Xyntha is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

Ask your pharmacy for Xyntha’s cash price, and one or two other pharmacies too.
Xyntha’s savings card works only with insurance from a job or one you bought.

Free from the maker, if you qualify Pfizer Patient Assistance Program. Meet the income requirements – Your annual household pre-tax income cannot exceed 300% of the Federal Poverty Level, adjusted for household size. Or call 1-844-989-7284.

See if you qualify

Compare every option

Brand nameXyntha

Authorized genericantihemophilic factor (recombinant)

Regular genericantihemophilic factor (recombinant)

What you’d pay

Cash priceAsk the pharmacy

Not soldThere isn’t one

Not soldAsk the pharmacy

Same as Xyntha?

The original

–

Brand nameThe maker’s card

Pfizer Factor Savings Card

Savings card from Pfizer

No insuranceNeeds insuranceNo cash price listed.

Insurance · as little as $0 a fill

The card takes up to $12,000 a year off your co-pay.

Or call 1-888-733-2030. See the offer on xyntha.com

In the maker’s words

“Eligible patients with commercial prescription drug insurance coverage for BeneFIX or Xyntha may pay as little as $0 per prescription fill.”

From the maker’s offer on xyntha.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Xyntha itself, from the same company, sold without the brand name, and usually for less. For now Xyntha is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Xyntha is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

Hemophilia A (treating and preventing bleeding)

What the FDA label says

XYNTHA is a recombinant antihemophilic factor indicated in adults and children with hemophilia A for on-demand treatment and control of bleeding episodes for perioperative management and for routine prophylaxis to reduce the frequency of bleeding episodes.
XYNTHA is not indicated in patients with von Willebrand's disease.

Source: the FDA label for Xyntha (Wyeth BioPharma Division of Wyeth Pharmaceuticals LLC), March 16, 2026. Full label on DailyMed

Good to know

“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/xyntha/