Xyrem

Regular genericMakers and their savings cards

2 companies sell a generic of Xyrem that the FDA rates a substitute. A pharmacy fills whichever one it stocks. 2 of them have their own savings cards or programs, listed first. Each works only with that maker’s version. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

It’s mostly filled by specialty pharmacies. Your prescriber’s office or insurer can tell you which one to use.

• Amneal Pharmaceuticals500 mg/mL

  Amneal Sodium Oxybate Oral Solution Copay Card

  For sodium oxybate oral solution 0.5 g/mL

  With commercial insurance as little as $0 a month

  Sign up on amneal.com

  In the maker’s words

  “Eligible, commercially insured patients may receive their Amneal Sodium Oxybate Oral Solution monthly prescription for $0.”

  Product page on amneal.com

  How it looks, what’s in it, NDCs

  500 mg/mL Clear

  Package	NDC
  Carton of 180 mL	65162-065-87

  Inactive ingredients: malic acid, sodium propylparaben, sodium hydroxide, water

  FDA label

• Camber Pharmaceuticals0.5 g/mL

  Made by Ascent Pharmaceuticals

  Camber Copay Assistance Program (Camber Pharmaceuticals Co-Pay Program)

  “To help alleviate the burden some drug prices create, Camber has made a copayment assistance program to help offset rising drug prices.” (patients not covered by any federal or state healthcare program (Medicare, Medicaid, Medigap, VA/DOD, TRICARE excluded); page says 'All non-excluded patients are eligible')

  Sign up

  Product page on camberpharma.com

  How it looks, what’s in it, NDCs

  0.5 g/mL

  Package	NDC
  Carton of 180 mL	31722-891-18

  Inactive ingredients: water, malic acid

  FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.