How to pay the least
From
$4 for 30 tablets
Generic lisinopril and hydrochlorothiazide at Walmart. Pick the strength on your label above for its own price.
- Ask your prescriber to send the prescription to your nearest Walmart. Or ask the store’s pharmacy to transfer it from your pharmacy.Find the nearest store
- Ask for generic lisinopril and hydrochlorothiazide.See Walmart’s price list
Rather have it mailed? From $8 a month from Rx Outreach, by mail. Make a free account, then have your prescription sent there.
Open Rx OutreachA regular generic has the same active ingredient as Zestoretic, and the FDA requires it to work the same way.
Compare every option
Details for each option
Brand nameNo maker’s card
We didn’t find a savings card or cash price from Zestoretic’s maker. Ask the pharmacy for Zestoretic’s cash price. With insurance, ask what your plan charges.
Authorized genericNot sold
There isn’t one. An authorized generic is Zestoretic itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.
Regular genericWhere to buy it
Pharmacies’ own cash prices for generic lisinopril and hydrochlorothiazide, lowest first.
Pick up in storeDelivered
- Delivered: Amazon Pharmacy $3.98for 30 tablets10 mg / 12.5 mg, 20 mg / 12.5 mg, 20 mg / 25 mgPrime members only · $139 a year · Free delivery · Prime price: limits on some medicines if you're over 65 or have Medicare, Medicaid or TRICARE
- Pick up in store: Walmart $4for 30 tablets20 mg / 25 mg90 tablets: $10Not in North Dakota; prices may be higher in some states, like California and MinnesotaFind the nearest store
- Pick up in store: Costco $14.79for 90 tablets20 mg / 12.5 mgMembers only · $65 a yearFind the nearest store
- Delivered: Costco $14.79for 90 tablets20 mg / 12.5 mgMembers only · $65 a year · Plus shipping
- Delivered: Cost Plus Drugs from $5.45for 30 tablets10 mg / 12.5 mg $5.45 · 20 mg / 12.5 mg $5.58 · 20 mg / 25 mg $5.59Plus $5.25 shipping
- Delivered: Marley Drug $37for a 6-month supplyNot every strength is on its list12-month supply: $70Shipping included
- Delivered: Rx Outreach $8a month10 mg / 12.5 mg, 20 mg / 12.5 mg, 20 mg / 25 mg90-day supply: $10Free delivery
- Pick up in store: Walgreens + Optum Perks $12.02for 30 tablets20 mg / 25 mgFree Optum Perks coupon · not with insuranceFind the nearest store
- Pick up in store: Team Cuban Card from $13.64for 30 tablets10 mg / 12.5 mg $13.64 · 20 mg / 12.5 mg $13.77 · 20 mg / 25 mg $13.81Free card · Kroger, Albertsons, Safeway, Meijer and many local pharmaciesFind a pharmacy that takes it
- Delivered: Optum Perks $14.03for 30 tablets20 mg / 25 mgPlus $5 shipping · Not with insurance
- Pick up in store: CVS Pharmacy + Optum Perks $18.89for 30 tablets20 mg / 25 mgFree Optum Perks coupon · not with insuranceFind the nearest store
- Pick up in store: Sam's Club See its pricePlus members only · $120 a yearFind the nearest store
From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.
About these prices
Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.
Regular genericWho makes it
5 companies sell a generic of Zestoretic that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.
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Actavis PharmaAll 3 strengths
Has dyes: FD&C Red No. 40, FD&C Blue No. 2--aluminum lake · Made by Watson Laboratories
How it looks, what’s in it, NDCs
10 mg / 12.5 mg Pink, round, 8 mm, marked “WATSON / 860”
Package NDC Bottle of 100 0591-0860-01 Bottle of 500 0591-0860-05 20 mg / 12.5 mg Light blue, round, 10 mm, marked “WATSON / 861”
Package NDC Bottle of 100 0591-0861-01 Bottle of 500 0591-0861-05 20 mg / 25 mg Pink, round, 10 mm, marked “WATSON / 862”
Package NDC Bottle of 100 0591-0862-01 Bottle of 500 0591-0862-05 Inactive ingredients: silicon dioxide, dibasic calcium phosphate dihydrate, FD&C Red No. 40, magnesium stearate, mannitol, starch, corn, FD&C Blue No. 2--aluminum lake
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CiplaAll 3 strengths
Made by Invagen Pharmaceuticals
How it looks, what’s in it, NDCs
10 mg / 12.5 mg Peach, round, 6 mm, marked “IG / 446”
Package NDC Bottle of 90 69097-968-05 Bottle of 100 69097-968-07 Bottle of 500 69097-968-12 Bottle of 1000 69097-968-15 20 mg / 12.5 mg White to off-white, round, 8 mm, marked “IG / 447”
Package NDC Bottle of 90 69097-969-05 Bottle of 100 69097-969-07 Bottle of 500 69097-969-12 Bottle of 1000 69097-969-15 20 mg / 25 mg Peach, round, 8 mm, marked “IG / 448”
Package NDC Bottle of 90 69097-971-05 Bottle of 100 69097-971-07 Bottle of 500 69097-971-12 Bottle of 1000 69097-971-15 Inactive ingredients: anhydrous dibasic calcium phosphate, mannitol, starch, corn, magnesium stearate, ferric oxide yellow, ferric oxide red
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Exelan PharmaceuticalsAll 3 strengths
Made by Invagen Pharmaceuticals
How it looks, what’s in it, NDCs
10 mg / 12.5 mg Pink, round, 6 mm, marked “IG / 446”
Package NDC Bottle of 90 76282-446-90 Bottle of 100 76282-446-01 Bottle of 500 76282-446-05 Bottle of 1000 76282-446-10 20 mg / 12.5 mg White to off-white, round, 8 mm, marked “IG / 447”
Package NDC Bottle of 90 76282-447-90 Bottle of 100 76282-447-01 Bottle of 500 76282-447-05 Bottle of 1000 76282-447-10 20 mg / 25 mg Pink, round, 8 mm, marked “IG / 448”
Package NDC Bottle of 90 76282-448-90 Bottle of 100 76282-448-01 Bottle of 500 76282-448-05 Bottle of 1000 76282-448-10 Inactive ingredients: anhydrous dibasic calcium phosphate, mannitol, starch, corn, magnesium stearate, ferric oxide yellow, ferric oxide red
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Lupin PharmaceuticalsAll 3 strengths
Has a dye: FD&C Blue No. 2
How it looks, what’s in it, NDCs
12.5 mg / 10 mg Blue, hexagon (6 sided), 7 mm, marked “LL / B01”
Package NDC Bottle of 100 68180-518-01 Bottle of 500 68180-518-02 Pouch of 5000 68180-518-30 12.5 mg / 20 mg Yellow, round, 8 mm, marked “LL / B02”
Package NDC Bottle of 100 68180-519-01 Bottle of 500 68180-519-02 Pouch of 5000 68180-519-30 25 mg / 20 mg Orange, round, 8 mm, marked “LL / B03”
Package NDC Bottle of 100 68180-520-01 Bottle of 500 68180-520-02 Pouch of 5000 68180-520-30 Inactive ingredients: anhydrous dibasic calcium phosphate, FD&C Blue No. 2, mannitol, starch, corn, magnesium stearate, aluminum oxide, ferric oxide yellow, ferric oxide red
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Solco HealthcareAll 3 strengths
Made by Prinston Pharmaceutical
How it looks, what’s in it, NDCs
10 mg / 12.5 mg White to off-white, round, 6 mm, marked “H150”
Package NDC Bottle of 100 43547-420-10 Bottle of 500 43547-420-50 Bottle of 1000 43547-420-11 20 mg / 12.5 mg Yellow, round, 8 mm, marked “H151”
Package NDC Bottle of 100 43547-421-10 Bottle of 500 43547-421-50 Bottle of 1000 43547-421-11 20 mg / 25 mg Pink mottled, round, 8 mm, marked “H152”
Package NDC Bottle of 100 43547-422-10 Bottle of 500 43547-422-50 Bottle of 1000 43547-422-11 Inactive ingredients: dibasic calcium phosphate dihydrate, magnesium stearate, mannitol, starch, corn, ferric oxide yellow, ferric oxide red
Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.
What to say at the pharmacy
“Before you fill my Zestoretic, can you tell me what I’d pay for the brand and for a generic?”
Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.
What it’s used for
What the FDA label says
ZESTORETIC is indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including lisinopril and hydrochlorothiazide.
Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than 1 drug to achieve blood pressure goals. For specific advice on goals and management, see published guidelines, such as those of the National High Blood Pressure Education Program’s Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC).
Numerous antihypertensive drugs, from a variety of pharmacologic classes and with different mechanisms of action, have been shown in randomized controlled trials to reduce cardiovascular morbidity and mortality, and it can be concluded that it is blood pressure reduction, and not some other pharmacologic property of the drugs, that is largely responsible for those benefits. The largest and most consistent cardiovascular outcome benefit has been a reduction in the risk of stroke, but reductions in myocardial infarction and cardiovascular mortality also have been seen regularly.
Elevated systolic or diastolic pressure causes increased cardiovascular risk, and the absolute risk increase per mmHg is greater at higher blood pressures, so that even modest reductions of severe hypertension can provide substantial benefit. Relative risk reduction from blood pressure reduction is similar across populations with varying absolute risk, so the absolute benefit is greater in patients who are at higher risk independent of their hypertension (for example, patients with diabetes or hyperlipidemia), and such patients would be expected to benefit from more aggressive treatment to a lower blood pressure goal.
Some antihypertensive drugs have smaller blood pressure effects (as monotherapy) in black patients, and many antihypertensive drugs have additional approved indications and effects (e.g., on angina, heart failure, or diabetic kidney disease). These considerations may guide selection of therapy.
These fixed-dose combinations are not indicated for initial therapy (see DOSAGE AND ADMINISTRATION ).
In using ZESTORETIC, consideration should be given to the fact that an angiotensin-converting enzyme inhibitor, captopril, has caused agranulocytosis, particularly in patients with renal impairment or collagen vascular disease, and that available data are insufficient to show that lisinopril does not have a similar risk (see WARNINGS ).
In considering the use of ZESTORETIC, it should be noted that ACE inhibitors have been associated with a higher rate of angioedema in black than in nonblack patients (see WARNINGS, Lisinopril ).
Source: the FDA label for Zestoretic (Almatica Pharma Inc.), March 31, 2025. Full label on DailyMed
Good to know
- A regular generic may look different from Zestoretic. The FDA requires it to work the same way.
- We didn’t find a savings card from Zestoretic’s maker.
- Don’t stop or change a medicine without talking to your pharmacist or prescriber.
Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/zestoretic/