Zilretta savings card: as little as $0 an injection with commercial insurance

Zilretta is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

How to pay the least

Given by your care team

Billed by the clinic

Zilretta is given by a doctor or nurse, not picked up at a pharmacy.

Ask your care team or your plan what you’d pay before your visit.

Compare every option

Brand nameZilretta

Authorized generictriamcinolone acetonide extended-release injectable

Regular generictriamcinolone acetonide extended-release injectable

What you’d pay

Cash priceAsk the pharmacy

Not soldThere isn’t one

Not soldNone found

Same as Zilretta?

The original

–

Brand nameThe maker’s card

ZILRETTA Co-Pay Program

Savings card from Pacira BioSciences

No insuranceNeeds insuranceNo cash price listed.

Insurance · as little as $0 an injection

The card takes up to $1,000 a year off your co-pay.

Or call 1-844-353-9466.

In the maker’s words

“ZILRETTA Co-Pay Program patients may pay as little as $0 out of pocket for each ZILRETTA injection/treatment.”

From the maker’s offer on zilretta.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericNot sold

There isn’t one. An authorized generic is Zilretta itself, from the same company, sold without the brand name, and usually for less. For now Zilretta is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

We didn’t find one. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

Knee pain from osteoarthritis (wear-and-tear arthritis)

What the FDA label says

ZILRETTA is an extended-release synthetic corticosteroid indicated as an intra-articular injection for the management of osteoarthritis pain of the knee.

Limitation of Use

The efficacy and safety of repeat administration of ZILRETTA have not been demonstrated.

Source: the FDA label for Zilretta (Pacira Pharmaceuticals, Inc.), June 3, 2026. Full label on DailyMed

Good to know

“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to the clinic’s billing office.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/zilretta/