Zioptan vs. its authorized generic and generics

How to pay the least

Ask for the cash price

Generic tafluprost

No pharmacy we check posts a price for it.

Ask your pharmacy for the cash price of generic tafluprost.Find pharmacies near you
Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as Zioptan, and the FDA requires it to work the same way.

Compare every option

Brand nameZioptan

Authorized generictafluprost

Regular generictafluprost

What you’d pay

Cash priceAsk the pharmacyUsually the highest price

Cash priceAsk the pharmacyUsually among the lowest

Same as Zioptan?

The original

Same medicine

Same active ingredientFillers and dyes can differ

Brand nameThe maker’s card

Zioptan’s maker has a savings card that lowers what you pay at the pharmacy.

Thea Pharma Patient Savings Card

Savings card from Thea Pharma

No insuranceNeeds insuranceNo cash price listed.

Insurance · as little as $20 a month

The card takes up to $780 a year off your co-pay.

Or call 1-877-505-6985.

In the maker’s words

“For BETIMOL®, COSOPT® PF, and ZIOPTAN® patients pay as little as $20, with a $65 savings for a 30 day prescription, with an enrollment year maximum of $780.”

From the maker’s offer on theapharmainc.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericThe NDC to ask for

The same medicine as Zioptan, without the brand name. Give the pharmacy its NDC to get it.

tafluprost

Sold by

Prasco Laboratories

NDC to ask for

0.0045 mg/0.3 mLdrops
- 66993-429-3011-digit: 66993-0429-3030 single-use vials, 0.3 mL each

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Zioptan, can you tell me what I’d pay for the brand, for the authorized generic from Prasco Laboratories (NDC 66993-429-30), and for a regular generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

Zioptan doesn’t come in this strength, so there’s no brand label to compare.

Authorized generic package label from Prasco Laboratories — Authorized genericPrasco Laboratories

See the ingredients

Active: tafluprost 0.0045 mg/0.3 mL

Inactive:

Edetate disodium
Glycerin
Hydrochloric acid
Polysorbate 80
Sodium hydroxide
Sodium phosphate, monobasic, dihydrate
Water

Regular genericWho makes it

3 companies sell a generic of Zioptan that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

Ingenus Pharmaceuticals0.0015%

How it looks, what’s in it, NDCs

0.0015%

Package NDC
Carton of 9 mL 50742-339-30

Inactive ingredients: glycerin, sodium phosphate, monobasic, dihydrate, edetate disodium, polysorbate 80, hydrochloric acid, sodium hydroxide, water
FDA label
Micro Labs0.0045 mg/0.3 mL

Product page on microlabsusa.com

How it looks, what’s in it, NDCs

0.0045 mg/0.3 mL Colorless to light yellow viscous liquid

Package NDC
Carton of 4.5 mL 42571-264-26
Carton of 9 mL 42571-264-73
Carton of 27 mL 42571-264-74

Inactive ingredients: edetate disodium, glycerin, hydrochloric acid, polysorbate 80, sodium phosphate, monobasic, dihydrate, sodium hydroxide, water
FDA label
Sandoz0.0045 mg/0.3 mL

How it looks, what’s in it, NDCs

0.0045 mg/0.3 mL

Package NDC
Carton of 9 mL 0781-6184-87

Inactive ingredients: glycerin, sodium phosphate, monobasic, dihydrate, edetate disodium, polysorbate 80, hydrochloric acid, sodium hydroxide, water
FDA label

Package	NDC
Carton of 9 mL	50742-339-30

Package	NDC
Carton of 4.5 mL	42571-264-26
Carton of 9 mL	42571-264-73
Carton of 27 mL	42571-264-74

Package	NDC
Carton of 9 mL	0781-6184-87

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

Glaucoma and high eye pressure

What the FDA label says

ZIOPTAN is a prostaglandin analog indicated for reducing elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.

Source: the FDA label for Zioptan (Thea Pharma Inc.), April 23, 2026. Full label on DailyMed

Good to know

It may look different from Zioptan (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Cash prices can differ a lot from one pharmacy to the next, so it can pay to ask two. With insurance, what you pay depends on your plan.
If your pharmacy doesn’t stock it, they can often order it within a day or two.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/zioptan/