Zonalon vs. its authorized generic and generics

How to pay the least

Ask for the cash price

Generic doxepin

No pharmacy we check posts a price for it.

Ask your pharmacy for the cash price of generic doxepin.Find pharmacies near you
Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as Zonalon, and the FDA requires it to work the same way.

Compare every option

Brand nameZonalon

Authorized genericdoxepin

Regular genericdoxepin

What you’d pay

Cash priceAsk the pharmacyUsually the highest price

Cash priceAsk the pharmacyUsually among the lowest

Same as Zonalon?

The original

Same medicine

Same active ingredientFillers and dyes can differ

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Zonalon’s maker. Ask the pharmacy for Zonalon’s cash price. With insurance, ask what your plan charges.

Authorized genericThe NDC to ask for

The same medicine as Zonalon, without the brand name. Give the pharmacy its NDC to get it.

doxepin

Sold by

Mylan PharmaceuticalsThe company behind Zonalon

NDC to ask for

5%cream
- 0378-8117-4511-digit: 00378-8117-4545 g per tube

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Zonalon, can you tell me what I’d pay for the brand, for the authorized generic from Mylan Pharmaceuticals (NDC 0378-8117-45), and for a regular generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

Same active and inactive ingredients as Zonalon.

Authorized generic package label from Mylan Pharmaceuticals — Authorized genericMylan Pharmaceuticals

See the ingredients

Active: doxepin hydrochloride 5%

Inactive, on both labels:

Benzyl alcohol
Cetyl alcohol
Isopropyl myristate
PEG-10 glyceryl stearate
PEG-100 stearate
Petrolatum
Sorbitol
Titanium dioxide
Water

Regular genericWho makes it

2 companies sell a generic of Zonalon that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

Amneal Pharmaceuticals5%

How it looks, what’s in it, NDCs

5% White to off-white

Package NDC
Carton of 45 g 69238-1733-6

Inactive ingredients: sorbitol, cetyl alcohol, isopropyl myristate, glyceryl monostearate, peg-100 stearate, petrolatum, benzyl alcohol, titanium dioxide, water
FDA label
Teva Pharmaceuticals5%

How it looks, what’s in it, NDCs

5%

Package NDC
Carton of 45 g 0093-9609-95

Inactive ingredients: sorbitol solution, cetyl alcohol, isopropyl myristate, glyceryl monostearate, peg-100 stearate, white petrolatum, benzyl alcohol, titanium dioxide, water
FDA label

Package	NDC
Carton of 45 g	69238-1733-6

Package	NDC
Carton of 45 g	0093-9609-95

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

Short-term relief of itching from eczema or lichen simplex chronicus

What the FDA label says

PRUDOXIN® Cream is indicated for the short-term (up to 8 days) management of moderate pruritus in adult patients with atopic dermatitis or lichen simplex chronicus. (See DOSAGE AND ADMINISTRATION.)

Source: the FDA label for Prudoxin (Mylan Pharmaceuticals Inc.), June 29, 2017. Full label on DailyMed

Good to know

It may look different from Zonalon (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Cash prices can differ a lot from one pharmacy to the next, so it can pay to ask two. With insurance, what you pay depends on your plan.
If your pharmacy doesn’t stock it, they can often order it within a day or two.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/zonalon/