Zoryve

Generic name: roflumilast

Used for: Plaque psoriasis · Eczema (atopic dermatitis) · 1 more

How do you pay?

How to pay the least

Ask for the cash price

Zoryve

No generic is sold yet.

  1. Ask your pharmacy for Zoryve’s cash price, and one or two other pharmacies too.
  2. Zoryve’s savings card works only with insurance from a job or one you bought.

Compare every option

Question
Brand nameZoryve
Authorized genericroflumilast
Regular genericroflumilast
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldNone sold yet
Same as Zoryve?
The original
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–

Brand nameThe maker’s card

ZORYVE Direct Savings Card Program

Savings card from Arcutis Biotherapeutics

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a fill

Sign up on zoryve.com 

Or call 1-844-979-1288.

In the maker’s words

“Eligible patients may pay as little as $0 for each prescription fill, up to a Patient Total Program Savings determined by the program.”

From the maker’s offer on zoryve.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Zoryve itself, from the same company, sold without the brand name, and usually for less. For now Zoryve is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

No generic is sold yet. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

ZORYVE cream is a phosphodiesterase 4 inhibitor:

Plaque Psoriasis

  • ZORYVE cream, 0.3%, is indicated for the topical treatment of plaque psoriasis, including intertriginous areas, in adult and pediatric patients 2 years of age and older.

Atopic Dermatitis

  • ZORYVE cream, 0.15%, is indicated for the topical treatment of mild to moderate atopic dermatitis in adult and pediatric patients 6 years of age and older.
  • ZORYVE cream, 0.05%, is indicated for the topical treatment of mild to moderate atopic dermatitis in pediatric patients 2 to 5 years of age.

Source: the FDA label for Zoryve (Arcutis Biotherapeutics, Inc.), July 20, 2026. Full label on DailyMed 

Good to know

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/zoryve/