How do you pay?

How to pay the least

Ask for the cash price

Generic loteprednol etabonate and tobramycin

No pharmacy we check posts a price for it.

  1. Ask your pharmacy for the cash price of generic loteprednol etabonate and tobramycin.Find pharmacies near you 
  2. Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as Zylet, and the FDA requires it to work the same way.

Compare every option

Question
Brand nameZylet
Authorized genericloteprednol etabonate and tobramycin
Regular genericloteprednol etabonate and tobramycin
What you’d pay
Cash priceAsk the pharmacyUsually the highest price
Cash priceAsk the pharmacyUsually among the lowest
Cash priceAsk the pharmacyUsually among the lowest
Same as Zylet?
The original
Same medicine
Same active ingredientFillers and dyes can differ

Brand nameThe maker’s card

Zylet’s maker has a savings card that lowers what you pay at the pharmacy.

Bausch + Lomb Access Program (copay card)

Savings card from Bausch + Lomb

Zylet’s maker has a savings program. Its page doesn’t list a dollar amount.

Sign up on bausch.com 

From the maker’s site, checked November 2, 2026. Check the maker’s page for who can use it.

Authorized genericThe NDC to ask for

The same medicine as Zylet, without the brand name. Give the pharmacy its NDC to get it.

loteprednol etabonate and tobramycin

Sold by
  • Bausch & LombThe company behind Zylet
NDC to ask for
  • 0.5% / 0.3%drops
    • 82260-358-0511-digit: 82260-0358-055 mL per dropper bottle
    • 82260-358-1011-digit: 82260-0358-1010 mL per dropper bottle

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Zylet, can you tell me what I’d pay for the brand, for the authorized generic from Bausch & Lomb (NDC 82260-358-05), and for a regular generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

Zylet doesn’t come in this strength, so there’s no brand label to compare.

Authorized genericBausch & Lomb
See the ingredients

Active: loteprednol etabonate 0.5% · tobramycin 0.3%

Inactive:

  • Benzalkonium chloride
  • Edetate disodium
  • Glycerin
  • Povidone
  • Sodium hydroxide
  • Sulfuric acid
  • Tyloxapol
  • Water

Regular genericWho makes it

One company sells a generic of Zylet that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • Alembic Pharmaceuticals0.5% / 0.3%
    How it looks, what’s in it, NDCs

    0.5% / 0.3%

    PackageNDC
    Carton of 5 mL62332-801-05
    Carton of 10 mL62332-801-10

    Inactive ingredients: benzalkonium chloride, edetate disodium, glycerin, tyloxapol, povidone, sodium hydroxide, sulfuric acid, water

    FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

What the FDA label says

ZYLET is a combination of loteprednol etabonate, a corticosteroid, and tobramycin, an aminoglycoside antibacterial, indicated for steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists.

Source: the FDA label for Zylet (Bausch & Lomb Incorporated), April 30, 2022. Full label on DailyMed 

Good to know