Zynyz is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

How do you pay?

How to pay the least

Given by your care team

Billed by the clinic

Zynyz is given by a doctor or nurse, not picked up at a pharmacy.

  1. Ask your care team or your plan what you’d pay before your visit.

Compare every option

Question
Brand nameZynyz
Authorized genericretifanlimab-dlwr
Regular genericretifanlimab-dlwr
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldAsk the pharmacy
Same as Zynyz?
The original
–
–

Brand nameThe maker’s card

IncyteCARES Savings Program for ZYNYZ

Savings card from Incyte

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $15 a prescription

Sign up on incytecares.com 

Or call 1-855-452-5234.

In the maker’s words

“Eligible patients can receive ZYNYZ for as little as $15, subject to certain limits…”

From the maker’s offer on incytecares.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericNot sold

There isn’t one. An authorized generic is Zynyz itself, from the same company, sold without the brand name, and usually for less. For now Zynyz is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Zynyz is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

ZYNYZ is a programmed death receptor-1 (PD-1)–blocking antibody indicated:

Squamous Cell Carcinoma of the Anal Canal (SCAC)

  • in combination with carboplatin and paclitaxel for the first-line treatment of adult patients with inoperable locally recurrent or metastatic squamous cell carcinoma of the anal canal (SCAC).
  • as a single agent for the treatment of adult patients with locally recurrent or metastatic SCAC with disease progression on or intolerance to platinum-based chemotherapy.

Merkel Cell Carcinoma (MCC)

  • for the treatment of adult patients with metastatic or recurrent locally advanced Merkel cell carcinoma (MCC).

Source: the FDA label for Zynyz (Incyte Corporation), May 18, 2026. Full label on DailyMed 

Good to know