Aloxi vs. its authorized generic and generics

Aloxi is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

How to pay the least

Given by your care team

Billed by the clinic

Aloxi is given by a doctor or nurse, not picked up at a pharmacy.

Ask your care team or your plan what you’d pay before your visit.

Compare every option

Brand nameAloxi

Authorized genericpalonosetron

Regular genericpalonosetron

What you’d pay

Not soldNo longer sold

Cash priceAsk the pharmacyOften less than Aloxi

Cash priceAsk the pharmacyUsually the lowest

Same as Aloxi?

–

Same medicine

Same active ingredientFillers and dyes can differ

Brand nameNot sold

Aloxi itself isn’t sold as a prescription anymore. Its generic versions, if any, are in the other tabs.

See the authorized generic →

Authorized genericThe NDC to ask for

The same medicine as Aloxi, without the brand name. Give the pharmacy its NDC to get it.

palonosetron

Sold by

Cipla

Given by your care team

This is given by IV at a clinic or hospital, usually before chemotherapy. It isn’t picked up at a pharmacy.

NDC (for your care team)

0.25 mg/5 mLinjection
- 69097-927-3511-digit: 69097-0927-355 mL per vial

Source: FDA, updated October 30, 2026

What to ask your care team

“Which version of Aloxi do you use: the brand, the authorized generic or a regular generic? What would I pay for each?”

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

Aloxi itself isn’t sold anymore, so there’s no current brand label to compare. Here’s the authorized generic’s label.

Authorized generic package label from Cipla — Authorized genericCipla

See the ingredients

Active: palonosetron hydrochloride 0.25 mg/5 mL

Inactive:

Citric acid monohydrate
Edetate disodium
Mannitol
Sodium citrate
Water

Regular genericWho makes it

11 companies sell an FDA-rated generic of Aloxi. It’s given by your care team, who choose which one to use.

ApotexInjection 0.25 mg/5 mL

Made by Qilu Pharm Hainan

How it looks, what’s in it, NDCs

0.25 mg/5 mL

Package NDC
Carton of 5 mL 60505-6193-1
Carton of 50 mL 60505-6193-4

0.25 mg/5 mL

Package NDC
Carton of 5 mL 60505-6439-1

Inactive ingredients: mannitol, citric acid monohydrate, sodium citrate, water
FDA label
BluePoint LaboratoriesSolution 0.05 mg/mL · Injection 0.25 mg/5 mL

Made by Dr. Reddy’s Laboratories and Qilu Pharm Hainan

How it looks, what’s in it, NDCs

0.05 mg/mL

Package NDC
Carton of 5 mL 68001-355-25

0.25 mg/5 mL

Package NDC
Carton of 5 mL 68001-708-25

Inactive ingredients: mannitol, edetate disodium, sodium acetate, water, citric acid monohydrate, sodium citrate form
FDA label
Dr. Reddy’s LaboratoriesSolution 0.05 mg/mL

How it looks, what’s in it, NDCs

0.05 mg/mL

Package NDC
Carton of 5 mL 55111-694-07
Carton of 7.5 mL 55111-694-19

Inactive ingredients: mannitol, edetate disodium, sodium acetate, water
FDA label
EugiaSolution 0.25 mg/5 mL

Product page on eugiaus.com

How it looks, what’s in it, NDCs

0.25 mg/5 mL

Package NDC
Carton of 5 mL 55150-186-05

Inactive ingredients: mannitol, edetate disodium, trisodium citrate dihydrate, citric acid monohydrate, hydrochloric acid, sodium hydroxide, water
FDA label
Fresenius KabiSolution 0.25 mg/5 mL

Product page on fresenius-kabi.com

How it looks, what’s in it, NDCs

0.25 mg/5 mL

Package NDC
Carton of 50 mL 63323-673-89

0.25 mg/5 mL

Package NDC
Carton of 5 mL 63323-673-05

Inactive ingredients: mannitol, edetate disodium, trisodium citrate dihydrate, anhydrous citric acid, hydrochloric acid, sodium hydroxide
FDA label
Meitheal PharmaceuticalsSolution 0.25 mg/5 mL

Product page on meithealpharma.com

How it looks, what’s in it, NDCs

0.25 mg/5 mL

Package NDC
Carton of 5 mL 71288-409-05

Inactive ingredients: mannitol, edetate disodium, trisodium citrate dihydrate, citric acid monohydrate, hydrochloric acid, sodium hydroxide, water
FDA label
Mylan InstitutionalSolution 0.25 mg/5 mL

How it looks, what’s in it, NDCs

0.25 mg/5 mL

Package NDC
Carton of 5 mL 67457-317-25

Inactive ingredients: mannitol, edetate disodium, citric acid monohydrate, sodium citrate form, water, hydrochloric acid, sodium hydroxide
FDA label
NorthStar RxSolution 0.05 mg/mL

Made by Dr. Reddy’s Laboratories

Product page on northstarrxllc.com

How it looks, what’s in it, NDCs

0.05 mg/mL

Package NDC
Carton of 5 mL 16714-834-01

Inactive ingredients: mannitol, edetate disodium, sodium acetate, water
FDA label
Sagent PharmaceuticalsSolution 0.05 mg/mL

How it looks, what’s in it, NDCs

0.05 mg/mL

Package NDC
Carton of 5 mL 25021-783-05

Inactive ingredients: mannitol, edetate disodium, citric acid monohydrate, water, sodium hydroxide, hydrochloric acid, trisodium citrate dihydrate
FDA label
SandozSolution 0.25 mg/5 mL

How it looks, what’s in it, NDCs

0.25 mg/5 mL

Package NDC
Carton of 5 mL 0781-3312-75
Carton of 50 mL 0781-3312-95

Inactive ingredients: mannitol, edetate disodium, trisodium citrate dihydrate, citric acid monohydrate, hydrochloric acid, sodium hydroxide, water
FDA label
Teva Parenteral MedicinesSolution 0.25 mg/5 mL

Being phased out; sold until December 2026

How it looks, what’s in it, NDCs

0.25 mg/5 mL

Package NDC
Carton of 5 mL 0703-4094-01

Inactive ingredients: mannitol, edetate disodium, trisodium citrate dihydrate, citric acid monohydrate, water, hydrochloric acid, sodium hydroxide
FDA label

Package	NDC
Carton of 5 mL	60505-6193-1
Carton of 50 mL	60505-6193-4

Package	NDC
Carton of 5 mL	60505-6439-1

Package	NDC
Carton of 5 mL	68001-355-25

Package	NDC
Carton of 5 mL	68001-708-25

Package	NDC
Carton of 5 mL	55111-694-07
Carton of 7.5 mL	55111-694-19

Package	NDC
Carton of 5 mL	55150-186-05

Package	NDC
Carton of 50 mL	63323-673-89

Package	NDC
Carton of 5 mL	63323-673-05

Package	NDC
Carton of 5 mL	71288-409-05

Package	NDC
Carton of 5 mL	67457-317-25

Package	NDC
Carton of 5 mL	16714-834-01

Package	NDC
Carton of 5 mL	25021-783-05

Package	NDC
Carton of 5 mL	0781-3312-75
Carton of 50 mL	0781-3312-95

Package	NDC
Carton of 5 mL	0703-4094-01

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

What the FDA label says

Palonosetron Hydrochloride Injection is a serotonin-3 (5-HT3) receptor antagonist indicated in adults for:

Moderately emetogenic cancer chemotherapy - prevention of acute and delayed nausea and vomiting associated with initial and repeat courses
Highly emetogenic cancer chemotherapy - prevention of acute nausea and vomiting associated with initial and repeat courses
Prevention of postoperative nausea and vomiting (PONV) for up to 24 hours following surgery. Efficacy beyond 24 hours has not been demonstrated

Palonosetron Hydrochloride Injection is indicated in pediatric patients aged 1 month to less than 17 years for:

Prevention of acute nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy, including highly emetogenic cancer chemotherapy

Source: the FDA label for palonosetron hydrochloride (Cipla USA Inc.), January 13, 2022. Full label on DailyMed

Good to know

It may look different from Aloxi (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Coverage depends on your plan. Your care team or insurer can tell you what you’d pay.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/aloxi/