Match the strength and how many to your prescription label.
How to pay the least
From
$14.56 for 30 tablets
Generic doxycycline hyclate with the free Team Cuban Card, at pharmacies that take it. Pick the strength on your label above for its own price.
- Get the free Team Cuban Card. It costs nothing to sign up.See the price and get the card
- At a pharmacy that takes it, show the card and ask for generic doxycycline hyclate: from $14.56 for 30 tablets.Find a pharmacy that takes it
By mail, if you can wait a few days From $6.59 for 30 tablets, plus $5.25 shipping from Cost Plus Drugs, by mail. Make a free account there, and have the prescription sent there.
Open Cost Plus DrugsEvery company’s doxycycline hyclate is rated by the FDA to work the same, so any pharmacy can fill your prescription with the one it stocks.
Regular genericWhere to buy it
Pharmacies’ own cash prices for generic doxycycline hyclate, lowest first. Any of them can fill your prescription.
Pick up in storeDelivered
- Delivered: Cost Plus Drugs from $7.42for 30 tablets20 mg $7.42 · 50 mg $146.35 · 75 mg $17.63 · 100 mg $6.59 · 150 mg $20.70Plus $5.25 shipping
- Pick up in store: Costco $14.99for 60 tablets20 mgMembers only · $65 a yearFind the nearest store
- Delivered: Costco $17.98for 60 tablets20 mgMembers only · $65 a year · Plus shipping
- Pick up in store: Team Cuban Card from $14.56for 30 tablets20 mg $14.56 · 100 mg $15Free card · Kroger, Albertsons, Safeway, Meijer and many local pharmaciesFind a pharmacy that takes it
- Delivered: Amazon Pharmacy from $24.50for 30 tablets20 mg $24.50 · 100 mg $14.62Prime members only · $139 a year · Free delivery
- Pick up in store: Sam's Club See its pricePlus members only · $120 a yearFind the nearest store
From each pharmacy’s own site, read October 5, 2026. Confirm the price before you fill. Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.
Regular genericWho makes it
14 companies sell doxycycline hyclate in this form, each one rated by the FDA as a substitute for the others. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.
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Acella Pharmaceuticals100 mg
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Actavis Pharma100 mg
Being phased out; sold until February 2027
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Ajanta Pharma75 mg, 150 mg
Has dyes: FD&C Blue No. 2, FD&C Yellow No. 6
How it looks, what’s in it, NDCs
75 mg Blue, round, 8 mm, marked “DY / 2”
Package NDC Bottle of 60 27241-153-02 150 mg Yellowish-green, capsule, 16 mm, marked “D / Y / 1”
Package NDC Bottle of 60 27241-154-02 Inactive ingredients: microcrystalline cellulose, sodium lauryl sulfate, magnesium stearate, hypromellose, titanium dioxide, polyethylene glycol, FD&C Blue No. 2, FD&C Yellow No. 6, ferric oxide yellow
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Alembic Pharmaceuticals20 mg, 50 mg, 75 mg, 150 mg
Has dyes: FD&C Blue No. 1, FD&C Blue No. 2
How it looks, what’s in it, NDCs
20 mg
Package NDC Bottle of 60 62332-352-60 Bottle of 100 62332-352-31 Bottle of 1000 62332-352-91 50 mg
Package NDC Bottle of 60 62332-499-60 75 mg Teal, round, 8 mm, marked “L22”
Package NDC Bottle of 60 62332-387-60 Bottle of 1000 62332-387-91 150 mg Mossy-green, oval, 16 mm, marked “L / 2 / 3”
Package NDC Bottle of 60 62332-388-60 Bottle of 1000 62332-388-91 Inactive ingredients: microcrystalline cellulose, sodium lauryl sulfate, croscarmellose sodium, magnesium stearate, polyvinyl alcohol, titanium dioxide, polyethylene glycol 3350, talc, ferric oxide yellow, FD&C Blue No. 1, FD&C Blue No. 2
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Blu Pharmaceuticals100 mg
Made by Epic Pharma
Packages and NDCs
100 mg
Package NDC Bottle of 20 24658-310-20 Bottle of 30 24658-310-30 Bottle of 50 24658-310-50 Bottle of 100 24658-310-01 Bottle of 210 24658-310-21 Bottle of 300 24658-310-07 Bottle of 400 24658-310-08 Bottle of 500 24658-310-05 Bottle of 1000 24658-310-10 -
Chartwell RX20 mg, 50 mg, 100 mg
Packages and NDCs
20 mg
Package NDC Bottle of 90 62135-623-90 50 mg
Package NDC Bottle of 60 62135-625-60 100 mg
Package NDC Bottle of 20 62135-626-20 Bottle of 28 62135-626-28 Bottle of 50 62135-626-50 Bottle of 100 62135-626-01 Bottle of 120 62135-626-12 Bottle of 210 62135-626-23 Bottle of 300 62135-626-31 Bottle of 400 62135-626-40 Bottle of 500 62135-626-05 Bottle of 1000 62135-626-10 Bottle of 2000 62135-626-96 -
Cranbury Pharmaceuticals100 mg
Made by Changzhou Pharmaceutical Factory
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Epic Pharma20 mg, 100 mg
Packages and NDCs
20 mg
Package NDC Bottle of 100 42806-362-01 Bottle of 1000 42806-362-10 100 mg
Package NDC Bottle of 50 42806-310-50 Bottle of 100 42806-310-01 Bottle of 500 42806-310-05 -
Hikma Pharmaceuticals100 mg
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Larken Laboratories20 mg
Made by Pharmobedient Consulting
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Lupin Pharmaceuticals75 mg, 100 mg, 150 mg
Has dyes: FD&C Blue No. 1, FD&C Yellow No. 6, FD&C Blue No. 2 · Made by Novel Laboratories
How it looks, what’s in it, NDCs
75 mg Light-teal, round, 9 mm, marked “LU / C80”
Package NDC Bottle of 60 68180-653-07 100 mg
Package NDC Bottle of 50 43386-794-50 Bottle of 100 43386-794-01 Bottle of 500 43386-794-05 150 mg Mossy-green, oval, 16 mm, marked “C / C / C”
Package NDC Bottle of 60 68180-654-07 Inactive ingredients: cellulose, microcrystalline, croscarmellose sodium, FD&C Blue No. 1, FD&C Yellow No. 6, hypromellose 2910 (5 mpa.s), magnesium stearate, polyethylene glycol 3350, polyvinyl alcohol, sodium lauryl sulfate, talc, titanium dioxide, FD&C Blue No. 2, ferric oxide yellow
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Strides Pharma Science50 mg
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Sun Pharmaceutical Industries20 mg, 100 mg
Packages and NDCs
20 mg
Package NDC Bottle of 30 53489-647-07 Bottle of 60 53489-647-06 Bottle of 90 53489-647-90 Bottle of 100 53489-647-01 Bottle of 250 53489-647-03 Bottle of 500 53489-647-05 Bottle of 1000 53489-647-10 100 mg
Package NDC Bottle of 50 53489-120-02 Bottle of 100 53489-120-01 Bottle of 500 53489-120-05 -
Viona Pharmaceuticals100 mg
Made by Zydus Lifesciences
Packages and NDCs
100 mg
Package NDC Bottle of 50 72578-001-18 Bottle of 100 72578-001-01 Carton of 100 72578-001-77 Bottle of 500 72578-001-05 Bottle of 1000 72578-001-10
Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.
What to say at the pharmacy
“Before you fill it, what would I pay for generic doxycycline hyclate?”
Paying cash? Ask for the cash price. With insurance, ask what your plan charges.
Good to know
- Different companies’ doxycycline hyclate can look different. The FDA requires each to work the same way.
- Don’t stop or change a medicine without talking to your pharmacist or prescriber.