Nexium

Generic name: esomeprazole

Used for: Heartburn and acid reflux (GERD) · Erosive esophagitis (acid damage to the esophagus) · Lowering the risk of stomach ulcers from NSAID pain relievers · H. pylori infection and ulcers · Too much stomach acid (such as Zollinger-Ellison syndrome) · 4 more

How do you pay?

How to pay the least

From

$11.08 for 30 capsules delivered ($5.83 plus $5.25 shipping)

Generic esomeprazole DR from Cost Plus Drugs, by mail. Pick the strength on your label above for its own price.

  1. Make a free account on costplusdrugs.com. Ask your prescriber to send the prescription there, or Cost Plus Drugs can transfer it.Open Cost Plus Drugs 
  2. Order generic esomeprazole DR. It comes by mail.

Need it today? From $14.24 for 30 capsules with the free Team Cuban Card, at pharmacies that take it. Get the free card and show it there.

See the price and get the card 

Sold without a prescription Esomeprazole DR is also sold over the counter (20 mg: Nexium 24HR and store brands). Ask your pharmacist or prescriber whether it would do for you.

A regular generic has the same active ingredient as Nexium, and the FDA requires it to work the same way.

Compare every option

Question
Brand nameNexium
Authorized genericesomeprazole
Regular genericesomeprazole
What you’d pay
At least$260for 30 capsules; pharmacies pay this
Not soldThere isn’t one
From$11.08for 30 capsules at Cost Plus Drugs, with shipping
Same as Nexium?
The original
–
Same active ingredientFillers and dyes can differ

Brand nameThe maker’s card

NEXIUM Savings Card

Savings card from AstraZeneca

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $15 a month

The card takes up to $175 a month off your co-pay.

Print the card (PDF) 

Or call 1-855-687-2144. See the offer on purplepill.com

In the maker’s words

“may pay as low as $15 for each 30-day supply, subject to a maximum savings limit of $175…”

From the maker’s offer on purplepill.com, checked October 27, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Nexium itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.

See the regular generic →

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic esomeprazole, lowest first.

Pick up in storeDelivered

From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericWho makes it

16 companies sell a generic of Nexium that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • Ascend LaboratoriesDR capsule 20 mg, 40 mg · Capsule 20 mg, 40 mg

    Has dyes: FD&C Blue No. 1, FD&C Red No. 40 · Made by Alkem Laboratories and Indchemie Health Specialties

    How it looks, what’s in it, NDCs

    20 mg DARK BLUE, capsule, 4 mm, marked “ESO / 20”

    PackageNDC
    Bottle of 3067877-478-30
    Bottle of 9067877-478-90
    Carton of 10067877-478-38
    Bottle of 50067877-478-05
    Bottle of 100067877-478-10

    20 mg Blue, capsule, 14 mm, marked “ESOM / 20”

    PackageNDC
    Bottle of 3067877-571-30
    Bottle of 9067877-571-90
    Carton of 10067877-571-38
    Bottle of 50067877-571-05
    Bottle of 100067877-571-10

    40 mg DARK BLUE, capsule, 3 mm, marked “ESO / 40”

    PackageNDC
    Bottle of 3067877-479-30
    Bottle of 9067877-479-90
    Carton of 10067877-479-38
    Bottle of 50067877-479-05
    Bottle of 100067877-479-10

    40 mg Blue, capsule, 16 mm, marked “ESOM / 40”

    PackageNDC
    Bottle of 3067877-572-30
    Bottle of 9067877-572-90
    Carton of 10067877-572-38
    Bottle of 50067877-572-05
    Bottle of 100067877-572-10

    Inactive ingredients: beet, hypromellose 2910 (5 mpa.s), poloxamer 188, meglumine, methyl alcohol, methylene chloride, talc, magnesium stearate, isopropyl alcohol, methacrylic acid and ethyl acrylate copolymer, triethyl citrate, glyceryl monostearate, silicon dioxide, gelatin, FD&C Blue No. 1, FD&C Red No. 40, titanium dioxide, sodium lauryl sulfate, shellac, alcohol, butyl alcohol, propylene glycol, ammonia, ferric oxide yellow, hypromellose, glyceryl mono- and dicaprylocaprate, potassium hydroxide, sucrose

    FDA label

  • Aurobindo PharmaDR granules 5 mg, 10 mg, 20 mg, 40 mg · DR capsule 20 mg, 40 mg

    Product page on aurobindousa.com

    How it looks, what’s in it, NDCs

    5 mg White to off white and pale yellow

    PackageNDC
    Carton of 3059651-802-30

    10 mg White to off white and pale yellow

    PackageNDC
    Carton of 3059651-803-30

    20 mg White, capsule, 14 mm, marked “I81”

    PackageNDC
    Carton of 1459651-561-14
    Bottle of 3059651-561-30
    Bottle of 9059651-561-90
    Bottle of 10059651-561-01
    Bottle of 100059651-561-99

    20 mg White to off white and pale yellow

    PackageNDC
    Carton of 3059651-804-30

    20 mg White, capsule, 14 mm, marked “I81”

    PackageNDC
    Bottle of 3065862-783-30
    Bottle of 9065862-783-90
    Bottle of 10065862-783-01
    Carton of 10065862-783-78
    Bottle of 100065862-783-99

    40 mg White, capsule, 18 mm, marked “I82”

    PackageNDC
    Bottle of 3059651-562-30
    Bottle of 9059651-562-90
    Bottle of 10059651-562-01
    Carton of 10059651-562-78
    Bottle of 100059651-562-99

    40 mg White to off white and pale yellow

    PackageNDC
    Carton of 3059651-805-30

    40 mg White, capsule, 18 mm, marked “I82”

    PackageNDC
    Bottle of 3065862-784-30
    Bottle of 9065862-784-90
    Bottle of 10065862-784-01
    Carton of 10065862-784-78
    Bottle of 100065862-784-99

    Inactive ingredients: anhydrous citric acid, crospovidone (35 .mu.m), anhydrous dextrose, ferric oxide yellow, hydroxypropyl cellulose (20000 wamw), hydroxypropyl cellulose (110000 wamw), hypromellose 2910 (3 mpa.s), magnesium carbonate, magnesium oxide, methacrylic acid and ethyl acrylate copolymer, polysorbate 80, sodium lauryl sulfate, glyceryl mono- and dipalmitostearate, dextrose form, starch, corn, sucrose, talc, triethyl citrate, xanthan gum, silicon dioxide, hydroxypropyl cellulose (1600000 wamw), titanium dioxide, gelatin, butyl alcohol, alcohol, isopropyl alcohol, propylene glycol, shellac, ammonia, glyceryl cocoate

    FDA label

  • Biocon PharmaDR capsule 20 mg, 40 mg

    Made by Graviti Pharmaceuticals

    How it looks, what’s in it, NDCs

    20 mg White opaque cap, capsule, 14 mm, marked “186 / 20 / mg”

    PackageNDC
    Bottle of 3070377-055-11
    Bottle of 9070377-055-12
    Bottle of 100070377-055-13

    40 mg White opaque cap, capsule, 16 mm, marked “187 / 40 / mg”

    PackageNDC
    Bottle of 3070377-056-11
    Bottle of 9070377-056-12
    Bottle of 100070377-056-13

    Inactive ingredients: ammonia, ferrosoferric oxide, gelatin, glyceryl mono and dipalmitostearate, hydroxypropyl cellulose (110000 wamw), hypromellose 2910 (5 mpa.s), magnesium stearate, methacrylic acid and ethyl acrylate copolymer, polysorbate 80, potassium hydroxide, propylene glycol, shellac, sodium lauryl sulfate, talc, titanium dioxide, triethyl citrate

    FDA label

  • Camber PharmaceuticalsDR capsule 20 mg, 40 mg

    Made by Hetero Labs

    Product page on camberpharma.com

    How it looks, what’s in it, NDCs

    20 mg White, capsule, 14 mm, marked “H / E2”

    PackageNDC
    Bottle of 3031722-664-30
    Bottle of 9031722-664-90
    Bottle of 100031722-664-10

    40 mg White, capsule, 16 mm, marked “H / E3”

    PackageNDC
    Bottle of 3031722-665-30
    Bottle of 9031722-665-90
    Bottle of 100031722-665-10

    Inactive ingredients: hypromellose 2910 (5 mpa.s), talc, triethyl citrate, polysorbate 80, hydroxypropyl cellulose, magnesium stearate, methacrylic acid - ethyl acrylate copolymer (1:1) type a, glyceryl monostearate, gelatin, titanium dioxide, sodium lauryl sulfate, shellac, propylene glycol, ammonia, ferrosoferric oxide, potassium hydroxide, sucrose, starch, corn, dimethicone

    FDA label

  • CiplaSuspension 2.5 mg, 5 mg, 20 mg, 40 mg · ER granules 10 mg
    How it looks, what’s in it, NDCs

    2.5 mg White to pale brownish

    PackageNDC
    Carton of 3069097-507-31

    5 mg White to pale brownish

    PackageNDC
    Carton of 3069097-508-31

    10 mg White to pale brownish

    PackageNDC
    Carton of 3069097-527-34

    20 mg White to pale brownish

    PackageNDC
    Carton of 3069097-528-34

    40 mg White to pale brownish

    PackageNDC
    Carton of 3069097-529-34

    Inactive ingredients: anhydrous citric acid, crospovidone, anhydrous dextrose, ferric oxide yellow, hydroxypropyl cellulose (1600000 wamw), xanthan gum, hypromellose 2910 (15 mpa.s), magnesium stearate, glyceryl monostearate, polysorbate 80, triethyl citrate, water, talc, methacrylic acid and ethyl acrylate copolymer

    FDA label

  • Dr. Reddy’s LaboratoriesDR capsule 20 mg, 40 mg

    Has a dye: FD&C Blue No. 1

    How it looks, what’s in it, NDCs

    20 mg Light blue cap and dark blue body, capsule, 16 mm, marked “RDY / 492”

    PackageNDC
    Bottle of 3043598-509-30
    Bottle of 9043598-509-90
    Bottle of 100043598-509-10

    40 mg Light blue cap and dark blue body, capsule, 18 mm, marked “RDY / 493”

    PackageNDC
    Bottle of 3043598-510-30
    Bottle of 9043598-510-90
    Bottle of 100043598-510-10

    Inactive ingredients: glyceryl monostearate, hypromelloses, magnesium stearate, methacrylic acid, polysorbate 80, talc, triethyl citrate, gelatin, FD&C Blue No. 1, titanium dioxide, ammonia, ferrosoferric oxide, butyl alcohol, alcohol, isopropyl alcohol, propylene glycol, potassium hydroxide, shellac, hydroxypropyl cellulose (1600000 wamw), dimethicone, sucrose

    FDA label

  • Granules PharmaceuticalsDR capsule 20 mg, 40 mg

    Has a dye: FD&C Blue No. 1

    Product page on granulespharma.com

    How it looks, what’s in it, NDCs

    20 mg Blue, capsule, 14 mm, marked “G / 59”

    PackageNDC
    Bottle of 3070010-133-03
    Bottle of 9070010-133-09
    Bottle of 100070010-133-10

    40 mg White, capsule, 16 mm, marked “G / 60”

    PackageNDC
    Bottle of 3070010-134-03
    Bottle of 9070010-134-09
    Bottle of 100070010-134-10

    Inactive ingredients: hydroxypropyl cellulose (110000 wamw), hypromellose 2910 (5 mpa.s), magnesium stearate, methacrylic acid and ethyl acrylate copolymer, glyceryl mono and dipalmitostearate, polysorbate 80, dimethicone, sucrose, talc, triethyl citrate, FD&C Blue No. 1, gelatin, sodium lauryl sulfate, titanium dioxide, ferrosoferric oxide, potassium hydroxide, propylene glycol, ammonia, shellac

    FDA label

  • LannettDR capsule 20 mg, 40 mg

    Has dyes: FD&C Blue No. 1, FD&C Red No. 40

    Product page on lannett.com

    How it looks, what’s in it, NDCs

    20 mg Opaque dark blue cap and opaque white body, capsule, 14 mm, marked “KU / 820”

    PackageNDC
    Bottle of 3062175-820-32
    Bottle of 9062175-820-46
    Bottle of 100062175-820-43

    40 mg Opaque light blue cap and opaque white body, capsule, 16 mm, marked “KU / 840”

    PackageNDC
    Bottle of 3062175-840-32
    Bottle of 9062175-840-46
    Bottle of 100062175-840-43

    Inactive ingredients: alcohol, butyl alcohol, diglycerin, FD&C Blue No. 1, FD&C Red No. 40, gelatin, glyceryl citrate, hydroxide ion, hypromellose 2208 (100 mpa.s), isopropyl alcohol, magnesium stearate, methacrylic acid and ethyl acrylate copolymer, polysorbate 80, potassium hydroxide, propylene glycol, shellac, sodium lauryl sulfate, sugarcane, talc, titanium dioxide, triethyl citrate

    FDA label

  • Mylan PharmaceuticalsDR capsule 20 mg, 40 mg

    Product page on viatris.com

    How it looks, what’s in it, NDCs

    20 mg White opaque, capsule, 16 mm, marked “M150”

    PackageNDC
    Bottle of 300378-2350-93
    Bottle of 900378-2350-77

    40 mg White opaque, capsule, 19 mm, marked “M151”

    PackageNDC
    Bottle of 300378-2351-93
    Bottle of 900378-2351-77

    Inactive ingredients: ferrosoferric oxide, crospovidone (120 .mu.m), gelatin, hydroxypropyl cellulose, mannitol, methacrylic acid - ethyl acrylate copolymer (1:1) type a, potassium hydroxide, sucrose, propylene glycol, shellac, ammonia, talc, titanium dioxide, triethyl citrate, starch, corn

    FDA label

  • NorthStar RxDR capsule 20 mg, 40 mg

    Has a dye: FD&C Blue No. 1 · Made by Dr. Reddy’s Laboratories

    Product page on northstarrxllc.com

    How it looks, what’s in it, NDCs

    20 mg Light blue cap and dark blue body, capsule, 16 mm, marked “RDY / 492”

    PackageNDC
    Bottle of 3016714-979-01
    Bottle of 9016714-979-02

    40 mg Light blue cap and dark blue body, capsule, 18 mm, marked “RDY / 493”

    PackageNDC
    Bottle of 3016714-980-01
    Bottle of 9016714-980-02
    Bottle of 100016714-980-03

    Inactive ingredients: glyceryl monostearate, hypromelloses, magnesium stearate, methacrylic acid, polysorbate 80, talc, triethyl citrate, gelatin, FD&C Blue No. 1, titanium dioxide, ammonia, ferrosoferric oxide, butyl alcohol, alcohol, isopropyl alcohol, propylene glycol, potassium hydroxide, shellac, hydroxypropyl cellulose (1600000 wamw), dimethicone, sucrose

    FDA label

  • Rising Pharma HoldingsDR capsule 20 mg, 40 mg

    Has a dye: FD&C Blue No. 1 · Made by CSPC Ouyi Pharmaceutical

    How it looks, what’s in it, NDCs

    20 mg Blue, capsule, 14 mm, marked “OEA97 / 20mg”

    PackageNDC
    Bottle of 3064980-632-03
    Bottle of 9064980-632-09
    Bottle of 100064980-632-10

    40 mg Blue, capsule, 16 mm, marked “OEA96 / 40mg”

    PackageNDC
    Bottle of 3064980-633-03
    Bottle of 9064980-633-09
    Bottle of 100064980-633-10

    Inactive ingredients: FD&C Blue No. 1, gelatin, glyceryl monostearate, hydroxypropyl cellulose, hypromellose, methacrylic acid and ethyl acrylate copolymer, polysorbate 80, sodium bicarbonate, sodium lauryl sulfate, talc, titanium dioxide, triethyl citrate, ferrosoferric oxide, potassium hydroxide, propylene glycol, sucrose, shellac, starch, corn

    FDA label

  • Solco HealthcareDR capsule 20 mg, 40 mg

    Has dyes: FD&C Blue No. 1, FD&C Red No. 3 · Made by Prinston Pharmaceutical

    How it looks, what’s in it, NDCs

    20 mg Pink and white, capsule, 3 mm, marked “S001 / 20”

    PackageNDC
    Bottle of 3043547-001-03
    Bottle of 9043547-001-09

    40 mg Pink, capsule, 3 mm, marked “S002 / 40”

    PackageNDC
    Bottle of 3043547-002-03
    Bottle of 9043547-002-09
    Bottle of 100043547-002-11

    Inactive ingredients: FD&C Blue No. 1, FD&C Red No. 3, ferrosoferric oxide, gelatin, hydroxypropyl cellulose, hypromellose, magnesium stearate, methacrylic acid, polyethylene glycol, potassium hydroxide, propylene glycol, silicon dioxide, sucrose, talc, titanium dioxide, triethyl citrate

    FDA label

  • Somerset TherapeuticsDR capsule 20 mg, 40 mg

    Has dyes: FD&C Blue No. 1, FD&C Red No. 3 · Made by Guangzhou Novaken Pharm

    Product page on somersetpharma.com

    How it looks, what’s in it, NDCs

    20 mg Opaque standard blue cap, opaque powder blue body, capsule, 14 mm, marked “A109 / 20mg”

    PackageNDC
    Bottle of 3070069-814-30
    Bottle of 9070069-814-90
    Bottle of 100070069-814-10

    40 mg Opaque standard blue cap, opaque powder blue body, capsule, 16 mm, marked “A108 / 40mg”

    PackageNDC
    Bottle of 3070069-815-30
    Bottle of 9070069-815-90
    Bottle of 100070069-815-10

    Inactive ingredients: glyceryl monostearate, hypromellose, magnesium oxide, magnesium stearate, methacrylic acid - ethyl acrylate copolymer (1:1) type a, polysorbate 80, sodium lauryl sulfate, starch, corn, sucrose, talc, triethyl citrate, FD&C Blue No. 1, FD&C Red No. 3, ferrosoferric oxide, gelatin, potassium hydroxide, shellac, titanium dioxide

    FDA label

  • Sun Pharmaceutical IndustriesDR capsule 20 mg, 40 mg

    Has dyes: D&C Red No. 28, FD&C Blue No. 1, FD&C Red No. 40

    How it looks, what’s in it, NDCs

    20 mg Pink opaque, capsule, 14 mm, marked “RB / 66”

    PackageNDC
    Bottle of 3063304-734-30
    Bottle of 9063304-734-90
    Bottle of 100063304-734-10

    40 mg Pink opaque, capsule, 16 mm, marked “RB / 67”

    PackageNDC
    Bottle of 3063304-735-30
    Bottle of 9063304-735-90
    Bottle of 100063304-735-10

    Inactive ingredients: hydroxypropyl cellulose, hypromellose, magnesium stearate, methacrylic acid - ethyl acrylate copolymer (1:1) type a, talc, triethyl citrate, polysorbate 80, gelatin, shellac, potassium hydroxide, propylene glycol, ferrosoferric oxide, starch, corn, sucrose, D&C Red No. 28, FD&C Blue No. 1, FD&C Red No. 40, titanium dioxide

    FDA label

  • Torrent PharmaceuticalsDR granules 2.5 mg, 5 mg, 10 mg, 20 mg, 40 mg
    How it looks, what’s in it, NDCs

    2.5 mg Light Yellow

    PackageNDC
    Carton of 3013668-546-94

    5 mg Light Yellow

    PackageNDC
    Carton of 3013668-547-94

    10 mg Light yellow

    PackageNDC
    Carton of 3013668-548-94

    20 mg Light Yellow

    PackageNDC
    Carton of 3013668-549-94

    40 mg Light Yellow

    PackageNDC
    Carton of 3013668-550-94

    Inactive ingredients: citric acid monohydrate, crospovidone (35 .mu.m), dextrose monohydrate, ethylcellulose, ferric oxide yellow, glyceryl monostearate, hydroxypropyl cellulose (110000 wamw), magnesium oxide, magnesium stearate, methacrylic acid - ethyl acrylate copolymer (1:1) type a, polysorbate 80, povidone k90, silicon dioxide, sucrose, talc, triethyl citrate, xanthan gum

    FDA label

  • Zydus LifesciencesDR capsule 20 mg, 40 mg · DR granules 20 mg, 40 mg

    Has dyes: FD&C Blue No. 1, FD&C Red No. 3, D&C Red No. 28

    How it looks, what’s in it, NDCs

    20 mg DARK BLUE OPAQUE (CAP) and WHITE OPAQUE (BODY), capsule, 14 mm, marked “441 / 20mg”

    PackageNDC
    Bottle of 3068382-441-06
    Bottle of 9068382-441-16
    Bottle of 100068382-441-10

    20 mg WHITE TO PALE BROWN and PALE RED TO RED

    PackageNDC
    Carton of 3068382-848-94

    40 mg BLUE OPAQUE (CAP) and OPAQUE WHITE (BODY), capsule, 18 mm, marked “442 / 40mg”

    PackageNDC
    Bottle of 3068382-442-06
    Bottle of 9068382-442-16
    Bottle of 100068382-442-10

    40 mg WHITE TO PALE BROWN and PALE RED TO RED

    PackageNDC
    Carton of 3068382-849-94

    Inactive ingredients: FD&C Blue No. 1, FD&C Red No. 3, ferrosoferric oxide, gelatin, glyceryl mono- and dicaprylocaprate, hydroxypropyl cellulose (90000 wamw), magnesium oxide, magnesium stearate, mannitol, methacrylic acid, polysorbate 80, potassium hydroxide, povidone k30, propylene glycol, shellac, sodium lauryl sulfate, starch, corn, sucrose, talc, titanium dioxide, triethyl citrate, anhydrous citric acid, crospovidone, dextrose, ferric oxide red, glyceryl monostearate, methacrylic acid and ethyl acrylate copolymer, povidone, strawberry, xanthan gum, D&C Red No. 28, hydroxypropyl cellulose (type e), methacrylic acid - ethyl acrylate copolymer (1:1) type a

    FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What to say at the pharmacy

“Before you fill my Nexium, can you tell me what I’d pay for the brand and for a generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

What it’s used for

What the FDA label says

NEXIUM is a proton pump inhibitor (PPI).

NEXIUM delayed-release capsules and NEXIUM for delayed-release oral

suspension are indicated for the:

  • Short-term treatment in the healing of erosive esophagitis (EE) in adults and pediatric patients 12 years to 17 years of age.
  • Maintenance of healing of EE in adults.
  • Short-term treatment of heartburn and other symptoms associated GERD in adults and pediatric patients 12 years to 17 years of age.
  • Risk reduction of nonsteroidal anti-inflammatory drugs (NSAID)-associated gastric ulcer in adults at risk for developing gastric ulcers due to age (60 years and older) and/or documented history of gastric ulcers.
  • Helicobacter pylori eradication in adult patients to reduce the risk of duodenal ulcer recurrence in combination with amoxicillin and clarithromycin.
  • Long-term treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome in adults.

NEXIUM for delayed-release oral suspension is indicated for the:

  • Short-term treatment in the healing of EE in pediatric patients 1 year to 11 years of age and of EE due to acid-mediated GERD in pediatric patients 1 month to less than 1 year of age.
  • Short-term treatment of heartburn and other symptoms associated with GERD in pediatric patients 1 year to 11 years of age.

Source: the FDA label for Nexium (AstraZeneca Pharmaceuticals LP), December 19, 2025. Full label on DailyMed 

Good to know

Prices checked October 27, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/nexium/