Olpruva savings card from the maker

How to pay the least

Ask for the cash price

Olpruva

The FDA has approved a generic, but it isn’t in pharmacies yet.

Ask your pharmacy for Olpruva’s cash price, and one or two other pharmacies too.

Compare every option

Brand nameOlpruva

Authorized genericsodium phenylbutyrate

Regular genericsodium phenylbutyrate

What you’d pay

Cash priceAsk the pharmacy

Not soldThere isn’t one

Not soldNot in stores yet

Same as Olpruva?

The original

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Brand nameThe maker’s card

AmplifyAssist commercial copay assistance program

Savings card from Acer Therapeutics (a Zevra Therapeutics company)

Olpruva’s maker has a savings program. Its page doesn’t list a dollar amount.

Or call 1-888-668-4198.

From the maker’s site, checked November 2, 2026. Check the maker’s page for who can use it.

Authorized genericNot sold

There isn’t one. An authorized generic is Olpruva itself, from the same company, sold without the brand name, and usually for less. For now Olpruva is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

The FDA has approved a generic, but it isn’t in pharmacies yet. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

Urea cycle disorders

What the FDA label says

OLPRUVA is a nitrogen-binding agent indicated as adjunctive therapy to standard of care, which includes dietary management, for the chronic management of adult and pediatric patients weighing 20 kg or greater and with a body surface area (BSA) of 1.2 m 2or greater, with urea cycle disorders (UCDs) involving deficiencies of carbamylphosphate synthetase (CPS), ornithine transcarbamylase (OTC), or argininosuccinic acid synthetase (AS).

Limitations of Use:

OLPRUVA is not indicated for the treatment of acute hyperammonemia.

Source: the FDA label for Olpruva (Acer Therapeutics Inc.), December 18, 2024. Full label on DailyMed

Good to know

“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Check the maker’s page for who can use it.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/olpruva/